Study highlights potential for using TMAO—a digestive by-product—to predict heart failure risk

New Cleveland Clinic and Tufts University research shows that elevated levels of the gut microbiome trimethylamine N-oxide (TMAO) pathway led to a higher risk of heart failure independent of other risk factors, according to a study of two large National Institutes of Health cohorts. The study was recently published in the journal Circulation: Heart Failure.

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