Chronic Endometritis associated with Caesarean Scar Diverticulum leading to prolonged menstruation and anemia: Study

Chronic Endometritis associated with Caesarean Scar Diverticulum leading to prolonged menstruation and anemia suggests a study published in the Journal of Reproductive Immunology.
A study was done to investigate the risk factors for Caesarean Scar Diverticulum (CSD) with Chronic Endometritis (CE) and the correlation between CE and clinical symptoms of CSD. The frequency of CE in 44 patients with CSD who underwent surgical treatment and 20 control women who underwent total hysterectomy was assessed and the clinical symptoms in the presence and absence of CE were compared. In accordance with the presence of one or more CD138-positive plasma cells per high-power field, CE was classified as mild or severe group. Results: According to multivariate analysis, the presence of mild CE (OR 8.963, 95 % CI 2.177–36.907, p = 0.002) or severe CE (OR 21.773, 95 % CI 2.285–207.419, p = 0.007) was significantly associated with CSD. Mild CE (OR 12.390, 95 % CI 1.158–132.511, p = 0.037) or severe CE (OR 22.463, 95 % CI 1.657–304.541, P = 0.019) or depth of diverticulum (OR 1.294, 95 % CI 1.003–1.668, p = 0.047) was associated with prolonged menstruation in patients with CSD. The degree of CE in patients with CSD was positively correlated with the days of prolonged menstruation (r = 0.552, p < 0.001) and negatively correlated with haemoglobin level (r = −0.408, p = 0.038). CE was associated with CSD and its clinical symptoms, including prolonged menstruation and decreased haemoglobin. The severity of clinical symptoms of CSD is associated with endometrial inflammation.
Reference:
Junchao Zhang, Jinfa Huang, Zexian Xu, Qian Yang, Lingling Zeng, Lei Zhou, Kaixian Deng,
The correlation between chronic endometritis and Caesarean scar diverticulum. Journal of Reproductive Immunology, Volume 166, 2024, 104324, ISSN 0165-0378,
https://doi.org/10.1016/j.jri.2024.104324.
(https://www.sciencedirect.com/science/article/pii/S0165037824001335)
Keywords:
Chronic, Endometritis, associated, Caesarean, Scar, Diverticulum, leading, prolonged, menstruation, anemia, study , Journal of Reproductive Immunology, Junchao Zhang, Jinfa Huang, Zexian Xu, Qian Yang, Lingling Zeng, Lei Zhou, Kaixian Deng