Influenza vaccine effective against severe illness in children
Influenza vaccine is effective for preventing severe influenza illness among children, according to a study published online Dec. 27 in JAMA Network Open.
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Archive for month: December, 2024
Bidirectional association found between rheumatoid arthritis, COPD
There is a bidirectional association between rheumatoid arthritis (RA) and chronic obstructive pulmonary disease (COPD), according to a review published online Dec. 1 in Frontiers in Immunology.
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Dr Sandip Shah takes charge as Chairperson of NABL
New Delhi: Dr Sandip Shah, an eminent medical professional and visionary leader, has been appointed as the Chairperson of the National Accreditation Board for Testing and Calibration Laboratories (NABL), a constituent board of the Quality Council of India (QCI).
NABL works to improve the quality of testing and calibration services, ensuring trust in the products and services used by consumers, businesses, and regulators.
Dr Shah, a Gold Medalist in MD Pathology and Bacteriology from BJ Medical College, Ahmedabad, has an extensive academic and professional background in pathology, molecular biology, and transplant immunology. He is the Joint Managing Director at Neuberg Diagnostics and the founder of Neuberg Supratech Reference Laboratories. Additionally, he serves as the Honorary Director at the Institute of Kidney Diseases and Research Center.
Also Read:Health Ministry collaborates with QCI to Improve Healthcare Quality in CGHS Hospitals
Dr Shah succeeds Prof. Subbanna Ayyappan in this role, bringing over 35 years of expertise in healthcare and diagnostics with a distinguished career in pathology, molecular biology, and transplant immunology.
He conceptualized and launched India’s first Drive-through COVID testing facility, which conducted over 3,500 tests at a single site. He has also contributed to healthcare innovation as a CAP Inspector and a visiting faculty member at IIM Ahmedabad. Dr. Shah has been a significant figure at NABL, having served as the Chair of the Medical Labs Accreditation Improvement Committee (MLAIC) and in various mentorship roles.
The Quality Council of India (QCI) is a premier autonomous body set up by the Government of India. QCI is responsible for creating a Quality Mindset and envisions to ensure quality across products and services that touch every citizen. As an independent and autonomous body, QCI creates a mechanism for independent third-party assessments of products, services, and processes, coordinating its activities through its constituent boards and divisions.
The Department for Promotion of Industry and Internal Trade (DPIIT), Ministry of Commerce & Industry, serves as the nodal point for QCI.
The National Accreditation Board for Testing and Calibration Laboratories (NABL) operates accreditation programs for laboratories, ensuring reliability and accuracy in testing and calibration. NABL’s services play a critical role in improving the global competitiveness of Indian industry and ensuring consumer safety.
Also Read:Dr Prem Nair appointed National President of Telemedicine Society of India
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KEA Releases PG Ayush Stray 2 Seat Matrix for 2024, 209 Seats Up For Grab
Karnataka- The Karnataka Authority Examinations (KEA) has released the Postgraduate (PG) Ayush Stray 2 Provisional seat matrix for the academic year 2024. The seat matrix has been released on its official website. Therefore, candidates can check and download the same from it.
As per the seat matrix, a total of 209 seats are vacant across 64 Ayush colleges in Karnataka. Below is the detailed seat matrix-
SEAT MATRIX
|
S.NO |
COLLEGE |
VACANT SEATS |
|
1 |
A.L.N Rao Memorial Ayurvedic Medical College. |
1 |
|
2 |
Jain AGM Ayurveda Medical College and Hospital, Varur. |
1 |
|
3 |
Muniyal Institute Of Ayurveda Medical Sciences. |
1 |
|
4 |
Alvas Ayurvedic Medical College. |
2 |
|
5 |
Sri Shivayogishwara Rural Ayurveda Medical College. |
1 |
|
6 |
DGM Ayurvedic Medical College. |
1 |
|
7 |
Bhagavan Mahaveer Jain Ayurvedic Medical College, PG Center. |
1 |
|
8 |
Rajiv Gandhi Ayurvedic Medical College. |
1 |
|
9 |
Ayurvedic Mahavidyalaya. |
1 |
|
10 |
Sri Basaveshwara Vidyavrdhaka Sangha Ayurvedic Medical College. |
1 |
|
11 |
DR. BNM Rural Ayurveda Medical College. |
1 |
|
12 |
Father Mullers Homoeopathy Medical College. |
3 |
|
13 |
Dr BD Jatti Homoeopathy Medical College. |
3 |
|
14 |
Ramakrishna Ayurveda Medical College. |
3 |
|
15 |
Sushrutha Ayurveda Medical College and Hospital. |
2 |
|
16 |
JSS Ayurvedic Medical College. |
4 |
|
17 |
S.D.M College of Ayurveda and Hospital. |
3 |
|
18 |
A.L.N Rao Memorial Ayurvedic Medical College. |
3 |
|
19 |
Muniyal Institute Of Ayurveda Medical Sciences. |
4 |
|
20 |
Karnataka Ayurvedic Medical College. |
2 |
|
21 |
S.D.M.Ayurveda College. |
3 |
|
22 |
Alvas Ayurvedic Medical College. |
11 |
|
23 |
Sri Shivayogishwara Rural Ayurveda Medical College. |
1 |
|
24 |
Ayurveda Mahavidyalaya Hospital. |
5 |
|
25 |
DGM Ayurvedic Medical College. |
2 |
|
26 |
Bhagavan Mahaveer Jain Ayurvedic Medical College, PG Center. |
2 |
|
27 |
Rajiv Gandhi Ayurvedic Medical College. |
2 |
|
28 |
Ayurvedic Mahavidyalaya. |
3 |
|
29 |
Sri Basaveshwara Vidyavrdhaka Sangha Ayurvedic Medical College. |
2 |
|
30 |
Gavisiddeshwara Society`s Ayurveda College. |
4 |
|
31 |
N.K.Jabashetty Ayurvedic Medical College. |
1 |
|
32 |
Sri Sri College Of Ayurvedic Science and Research Center. |
5 |
|
33 |
DR. B.N.M. RURAL AYURVEDA MEDICAL COLLEGE. |
4 |
|
34 |
H.K.D.E.Ts, Rajarajeshwari Ayurvedic Medical College and Hospital. |
1 |
|
35 |
Jain AGM Ayurveda Medical College and Hospital. |
1 |
|
36 |
Father Mullers Homoeopathy Medical College. |
10 |
|
37 |
A.M.Sheik Homoeopathy Medical College. |
3 |
|
38 |
Bharatesh Homoeopathy Medical College. |
2 |
|
39 |
Dr.B.D.Jatti Homoeopathy Medical College. |
3 |
|
40 |
H.K.E.Society Homoeopathy Medical College. |
4 |
|
41 |
Ramakrishna Ayurveda Medical College. |
4 |
|
42 |
Sushrutha Ayurveda Medical College and Hospital. |
1 |
|
43 |
JSS Ayurvedic Medical College. |
3 |
|
44 |
A.L.N Rao Memorial Ayurvedic Medical College. |
4 |
|
45 |
Muniyal Institute Of Ayurveda Medical Sciences. |
7 |
|
46 |
Karnataka Ayurvedic Medical College. |
3 |
|
47 |
Alvas Ayurvedic Medical College. |
16 |
|
48 |
Ayurveda Mahavidyalaya Hospital. |
3 |
|
49 |
DGM Ayurvedic Medical College. |
5 |
|
50 |
Bhagavan Mahaveer Jain Ayurvedic Medical College, PG Center. |
3 |
|
51 |
Rajiv Gandhi Ayurvedic Medical College. |
4 |
|
52 |
Ayurvedic Mahavidyalaya. |
3 |
|
53 |
Sri Basaveshwara Vidyavrdhaka Sangha Ayurvedic Medical College. |
3 |
|
54 |
Gavisiddeshwara Society`s Ayurveda College. |
2 |
|
55 |
N.K.Jabashetty Ayurvedic Medical College. |
2 |
|
56 |
DR. B.N.M. RURAL AYURVEDA MEDICAL COLLEGE. |
5 |
|
57 |
H.K.D.E.Ts, Rajarajeshwari Ayurvedic Medical College and Hospital. |
3 |
|
58 |
Jain AGM Ayurveda Medical College and Hospital. |
1 |
|
59 |
Father Mullers Homoeopathy Medical College. |
11 |
|
60 |
A.M.Sheik Homoeopathy Medical College. |
2 |
|
61 |
Bharatesh Homoeopathy Medical College. |
2 |
|
62 |
Dr.B.D.Jatti Homoeopathy Medical College. |
7 |
|
63 |
H.K.E.Society Homoeopathy Medical College. |
6 |
|
64 |
Luqman Unani Medical College. |
1 |
|
TOTAL |
209 |
To view the seat matrix, click the link below
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Lending Signatures, expired License: Maha Pathologist suspended for 3 years
Mumbai: Taking action against a pathologist for allowing to use her signature in multiple pathology reports from Private Labs even though she did not supervise those reports, the Maharashtra Medical Council (MMC) has removed her name from the Medical Register for three years.
MMC noted that while the doctor had multiple attachments with Private Pathology Labs, such laboratories were located at places which made it impossible for any individual to attend daily. Meanwhile, the name and signature of the doctor were used as.a routine as well as Insurance Claim reports.
Even though the doctor was suspended for six months back in the year 2021, she allegedly continued signing multiple pathology reports and when she was issued notice by the Commission, she chose not to respond to the same.
Apart from these allegations, the Council also found that the doctor had not responded to the communication/notices of the Council from 2019 and had not renewed the Registration since 2012. Further, she was found practicing in Maharashtra without any valid licence.
“Therefore, the Administrator of the Council, empowered u/sec 31 and MMC Act, hereby passes the order to remove the Registration/Name of RMP Dr. Sireesha Mohan (Reg. No. 63614) for the period of 3 (Three) years from Register maintained u/ sec 16 of MMC Act and informing the same to NMC for updating Registration details,” MMC mentioned in its order.
The complaint against the doctor was filed by Mr. Prasad Kulkarni back in 2019. He alleged that the doctor was involved in malpractices and insurance fraud as detected by a Private Insurance Fraud Detection Agency i.e. Bullet Health Care Pvt. Ltd. During the fraud detection of insurance claim cases, it was observed that the doctor had multiple attachments with Private Pathology Labs, whereas these labs were located at places which made it impossible for any individual to attend on daily basis.
After considering the complaint, MMC issued notice. However, the doctor did not reply to the notice. Thereafter, MMC held the hearings on various dates and after issuing due notices to both the parties as well, the doctor did not turn up and chose to remain absent. Considering this, the Committee decided to frame charge sheet and accordingly, the charge sheet was issued on 20.03.2020.
After the framing of charges, the matter was placed before the Executive Committee. However, for the said inquiry also, the doctor remained absent. After detailed discussions and deliberations, the Council decided to suspend her medical license. Accordingly, the council suspended her Registration under section 10 (d) of the MMC Act, 1965 through the order dated 02.12.2020. Accordingly, the doctor was refrained from doing any medical practice.
Following this, another inquiry was held on 15/05/2021, for which, the doctor again chose to remain absent. Considering her continuous absence and ignorance to the Council’s notices, the Council decided to take stern action against the doctor. Therefore, through the order dated 18/09/2021, MMC removed her registration for a period of six months. Since, the doctor had not preferred any appeal before the erstwhile MCI, now NMC, the MMC order was confirmed.
Also Read: Medical Council wrath on Pathologists for allowing use of Scanned Signatures
Medical Dialogues had earlier reported, that holding the Maharashtra-based pathologist Dr. Mohan guilty of gross violation of Professional code of ethics, MMC had taken action against her for certifying pathology lab reports without personal supervision and allowing private laboratories for using her scanned signatures. Back then, the Exective Committee of the Council had decided to remove her registration from the register for 6 months.
However, back in 2023, the complainant pointed out before the Commission that during the suspension period also, the doctor was found involved in signing of multiple pathology reports.
Taking note of this, MMC issued a notice to the doctor on 18/09/2023. Again, the doctor chose not to respond to the notice and “disobeyed the directions given by the Council.”
Further inquiry was held on 03/04/2024 and the complianant produced more evidence i.e. Pathology lab reports signed by the doctor during the removal period.
The council noted that the doctor did not respond to the notices issued by MMC, was practicing without valid licence and she also had not renewed her licence since 2012.
“Therefore, considering the nature of the complaint, suspension order as well as removal order 85 considering you have not responded to the communication/ notices of the council from 2019, neither you had renewed your Registration since 2012 and you were found practicing in the State of Maharashtra without valid licence. Further not communicated or attended enquiry held by the Council, it shows disrespect to the council. In view of above, your name and your Reg. No. 63614 is hereby removed for the period of 3 (Three) years from the medical register, thereby you have been refrained from doing any kind of medical practice and/or professional duty during the removal period. If found doing so, same may be treated practice by unregistered practitioner and liable for Criminal Action,” MMC mentioned in its order.
Accordingly, the MMC Administrator decided to remove the doctor’s registration or her name from the Register maintained u/ sec 16 of MMC Act for a period of three (3) years.
To view the MMC order, click on the link below:
https://medicaldialogues.in/pdf_upload/mmc-removal-order-of-dr-sireesha-mohan-266741.pdf
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Quack booked for running clinic at Kaimbwala Village
Chandigarh: A case has been registered against a quack for allegedly running a clinic without a valid medical degree near the bus stand in Kaimbwala village, Chandigarh. Authorities took action after receiving complaints about the individual providing medical services without proper qualifications.
The accused, who ran his Clinic near the Kaimbwala bus stand, has been charged under Section 318(4) of the Bharatiya Nyaya Sanhita (BNS) and Section 15(3) of the Indian Medical Council Act, 1956.
The case was initiated after a formal complaint was filed by Sadhu Ram, which was forwarded by the Director of Health and Family Welfare-cum-Convenor (CEA), UT Administration. The complaint alleged that the accused was practicing medicine illegally and had been misrepresenting himself as a qualified healthcare provider. This has raised concerns about public safety while opting for treatment.
Also Read: Quack practising as Ayurvedic doctor arrested in Odisha
As per the recent media report by Hindustan Times, the Bogus Doctors Checking Team (BDCT), in its report dated August 7, confirmed that Roshan lacked the requisite qualifications to practice medicine in Chandigarh.
Following the BDCT’s findings, Dr. Manju Shree, the Assistant Director (Homeopathy) and the Nodal Officer for the BDCT, formally requested the Senior Superintendent of Police (SSP) to register an FIR and take appropriate legal action against the accused.
In response to the request, police officials confirmed that an FIR was officially registered on Tuesday at the Sector 3 Police Station in Chandigarh.
Also Read: Quack under Telangana Medical Council’s radar for promoting self-styled dietary plans
Medical Dialogues had earlier reported that amid growing concerns over the increasing number of unqualified medical practitioners in Telangana, another quack has recently come under scrutiny. He is accused of treating patients at his clinic in Banjara Hills and is now being investigated by the Telangana Medical Council (TSMC).
Known as “Dr. VRK,” this individual has allegedly been providing unverified treatments and questionable medical advice to people. He allegedly promotes a self-styled “VRK Diet” which includes dietary recommendations and extensive prescriptions, particularly for conditions like type 1 diabetes, cancer cure, and reversal of chronic kidney disease.
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UT Administration Proposes Reclassification of PGI Chandigarh Services as Essential Under Haryana ESMA
Chandigarh: In a bid to ensure uninterrupted essential services, the Chandigarh Administration has written to the Post Graduate Institute of Medical Education and Research (PGIMER) to inquire if any of its services should be classified as ‘essential’ under the newly adopted Haryana Essential Services (Maintenance) Act (ESMA), 1974.
This move comes in response to the UT administration’s decision earlier this month to adopt the stricter Haryana ESMA, replacing the outdated East Punjab Essential Services (Maintenance) Act, of 1947. PGIMER recently witnessed strikes by healthcare professionals and other staff members.
Also Read: PGI Chandigarh’s SFC approves Faculty recruitment, Infrastructure Enhancement
Speaking to TOI, a UT official informed, “For the full effect of the ESMA Act, a service must be designated as ‘essential’. While PGIMER health services were classified as ‘essential’ under previous ESMA provisions, they need to be designated as ‘essential’ again to be covered under the more stringent Haryana ESMA.”
The Haryana ESMA is a much stronger version of the older East Punjab Essential Services (Maintenance) Act, 1947, and includes provisions that make offences related to strikes in essential sectors non-bailable.
Also Read: PGI doctor saves Former Army Official’s Life mid-air on Bengaluru-Delhi flight
According to TOI, unlike the existing provisions, which do not define ‘strike’, the Haryana law defines ‘strike’ as “the cessation of work by a body of persons employed in any employment or class of employment to which this Act applies, acting in combination, or a concerted refusal, or a refusal under a common understanding, of any number of persons, who are or were so employed to continue to work or to accept employment”.
In a proactive step to prevent any disruptions in power supply, the Chandigarh administration invoked the provisions of Section 4A of the Haryana ESMA. The UT administrator has officially prohibited strikes within the engineering department, specifically the electricity wing, for a period of six months, effective immediately.
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PCSK9 Inhibitors and Statins for lowering LDL Cholesterol Levels exhibit Long-Term Cognitive Safety: Study
A recent groundbreaking study published
in the journal NEJM Evidence found no association between exposure to very low
cholesterol levels achieved with PCSK9 inhibition and statin therapy and cognitive
impairment.
Concerns have been raised about
the cognitive safety of obtaining extremely low levels of low-density
lipoprotein (LDL) cholesterol through PCSK9 inhibition and statin therapy.
Although short-term studies are reassuring, the long-term effects of sustained
exposure to very low LDL cholesterol levels through combined PCSK9 inhibition
and statin therapy are uncertain. Hence, researchers conducted a prospective
study to assess the long-term effect of evolocumab on cognitive function.
The study included adults with
atherosclerotic cardiovascular disease who had completed a neurocognitive sub-study
(EBBINGHAUS) of a placebo-controlled evolocumab (FOURIER) trial and were
eligible for a long-term open-label extension. Cognitive function was assessed
every year. The primary endpoint was a change from baseline in executive
function within each group. A spatial working memory strategy index score was
used to measure the change in the scores. A range of 4-28 was given to the
scores, and lower scores indicated better performance.
Findings:
- About 473 of the 1974 patients in the parent
EBBINGHAUS study were enrolled and followed for a median of 5.1 years (maximum
follow-up since original random assignment 7.2 years). - The median age was 62; 70% were male, and 91%
were White. - At 12 weeks into the open-label extension
period, median LDL cholesterol across the overall population was 35 mg/dl
(interquartile range, 21–55 mg/dl). - There was no change in executive function in
patients treated with evolocumab during the open-label extension, either
patients who were initially randomly assigned to and continued evolocumab or
patients initially randomly assigned to placebo and then started on evolocumab. - The executive function scores were similar
between randomly assigned groups in the final study visit.
Thus, the study concluded that exposure
to low LDL cholesterol levels was not associated with cognitive impairment in
patients requiring aggressive lipid therapy. The study underscores the importance
of cognitive safety reassurance from long-term statin therapy. As the condition
is not compromised, rapid lipid-lowering agents can be used for long-term
adherence in needed individuals. However, researchers suggest further research
in diverse populations to explore the potential effects of these drugs.
Further reading: Zimerman A,
O’Donoghue ML, Ran X, et al. Long-Term Cognitive Safety of Achieving Very Low
LDL Cholesterol with Evolocumab. NEJM Evid.
2025;4(1):EVIDoa2400112. doi:10.1056/EVIDoa2400112.
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Cutaneous Carbonyl Stress Linked to Nerve Dysfunction and Neuropathy Risk in Recent-Onset Type 2 Diabetes: Study
Germany: A study published in Diabetes Care reveals that elevated cutaneous carbonyl stress is linked to slower nerve conduction in patients with recent-onset, well-controlled type 2 diabetes (T2D) and may predict neuropathic deficits over five years. The findings suggest that advanced glycation end products, formed as a result of carbonyl stress, could represent a potential target for preventing diabetic sensorimotor polyneuropathy.
Endogenous carbonyl stress contributes to the formation of advanced glycation end products (AGEs), which are considered potential targets for preventing or treating diabetic sensorimotor polyneuropathy (DSPN). To explore this, Gidon J. Bönhof, Department of Endocrinology and Diabetology, Medical Faculty, University Hospital Düsseldorf, Heinrich-Heine-University Düsseldorf, Düsseldorf, Germany, and colleagues aimed to investigate cutaneous carbonyl stress, oxidative stress, immune cell activity, and endothelial cell damage in early type 2 diabetes compared to individuals with normal glucose tolerance (NGT) by utilizing novel cutaneous biomarkers.
For this purpose, the researchers included 160 individuals recently diagnosed with type 2 diabetes (≤12 months) and 144 individuals with normal glucose tolerance from the baseline cohort of the German Diabetes Study. Nerve function was evaluated using electrophysiological assessments, quantitative sensory testing, and clinical evaluations. Skin biopsies were taken to examine intraepidermal nerve fiber density, AGEs autofluorescence, argpyrimidine area, and endothelial cell area. Additionally, skin autofluorescence was measured noninvasively using the AGE reader. A subgroup of 80 type 2 diabetes patients was reassessed after five years to monitor long-term changes.
Based on the study, the researchers reported the following findings:
- After adjusting for sex, age, HbA1c, LDL cholesterol, and BMI, argpyrimidine area was higher in recent-onset type 2 diabetes (17.5 ± 18.8%) compared to those with normal glucose tolerance (NGT) (11.7 ± 12.7%).
- AGEs autofluorescence showed an inverse correlation with nerve conduction, such as peroneal motor nerve conduction velocity (r = −0.346), in type 2 diabetes.
- AGEs autofluorescence was positively correlated with AGE reader measurements in type 2 diabetes (r = 0.358) but showed no such correlation in NGT.
- Higher baseline AGEs autofluorescence and lower endothelial cell area predict worsening of clinical and neurophysiological outcomes over five years.
The study showed that markers of cutaneous AGEs were linked to neurophysiological deficits in recent-onset type 2 diabetes and predicted their progression over five years, highlighting the role of carbonyl stress in the early development of diabetic sensorimotor polyneuropathy.
“Prospective analyses highlighted that cutaneous AGEs and reduced endothelial integrity may predict declining nerve function, supporting the role of carbonyl stress in the development and progression of DSPN and identifying it as a potential therapeutic target,” the researchers concluded.
Reference:
Gidon J. Bönhof, Alexander Strom, Tobias Jung, Kálmán B. Bódis, Julia Szendroedi, Robert Wagner, Tilman Grune, Michael Roden, Dan Ziegler; Cutaneous Carbonyl Stress Is Associated With Nerve Dysfunction in Recent-Onset Type 2 Diabetes. Diabetes Care 2024; dc241799. https://doi.org/10.2337/dc24-1799
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High Non-Fermented Milk Intake Linked to Increased Heart Disease Risk in Women, Study Finds
Sweden: A recent study involving over 100,000 participants suggests that non-fermented milk may increase the risk of ischemic heart disease (IHD), particularly in women, while no significant association was found in men. The researchers propose that metabolic pathways involving ACE2 and FGF21 may explain the observed association.
According to the researchers, regular milk consumption may negatively impact heart health in women, whereas fermented milk products seem to be safe. The findings were published online in BMC Medicine on November 8, 2024.
The impact of milk on the risk of ischemic heart disease and acute myocardial infarction (MI) remains unclear. To address this, Karl Michaëlsson, Medical Epidemiology, Department of Surgical Sciences, Uppsala University, Uppsala, Sweden, and colleagues aimed to explore the association between non-fermented and fermented milk consumption and these health outcomes, and investigate the relationship between milk intake and cardiometabolic-related proteins in plasma.
For this purpose, the researchers utilized data from two Swedish prospective cohort studies, which included 59,998 women and 40,777 men without IHD or cancer at baseline. Participants provided repeated measures of diet, lifestyle factors, and plasma proteomics data across two subcohorts. Through registry linkage, 17,896 IHD cases were documented during up to 33 years of follow-up, including 10,714 cases of myocardial infarction.
The researchers employed time-updated multivariable Cox regression analysis to examine the relationship between non-fermented or fermented milk intake and the risk of IHD or MI. Additionally, using high-throughput multiplex immunoassays, 276 cardiometabolic plasma proteins were measured, and multivariable-adjusted regression models with a discovery-replication design were used to explore protein associations with increasing milk consumption.
The following were the key findings of the study:
• The results for non-fermented milk intake varied by sex.
• In women, a pattern of increased risk of ischemic heart disease and myocardial infarction was observed with non-fermented milk intake greater than 1.5 glasses/day.
• Compared to an intake of 0.5 glass/day (100 mL/day), women who consumed:
• Two glasses/day had a multivariable-adjusted hazard ratio (HR) of 1.05 for IHD.
• Three glasses/day had an HR of 1.12 for IHD.•
• Four glasses/day had an HR of 1.21 for IHD.
• Similar findings were observed for whole, medium-fat, and low-fat m
• No increased risk of IHD was detected with higher milk intakes in men.
• Fermented milk intake was not associated with IHD or MI risk in either sex.
• Increasing non-fermented milk intake in women was strongly linked to higher plasma ACE2 levels and lower FGF21 concentrations.
“Our findings suggest a direct association between non-fermented milk intake, regardless of fat content, and ischemic heart disease in women at intakes exceeding 300 mL/day, but not in men. Fermented milk intake was not linked to IHD risk. Substitution analysis recommended that women opt for a higher intake of fermented milk rather than non-fermented milk,” the researchers wrote.
“Additionally, non-fermented milk consumption in women was associated with higher levels of ACE2 and lower levels of FGF21, two key cardiometabolic proteins with complex regulatory effects, implying potential pathogenic mechanisms underlying these results,” they concluded.
Reference:
Michaëlsson, K., Lemming, E.W., Larsson, S.C. et al. Non-fermented and fermented milk intake in relation to risk of ischemic heart disease and to circulating cardiometabolic proteins in swedish women and men: Two prospective longitudinal cohort studies with 100,775 participants. BMC Med 22, 483 (2024). https://doi.org/10.1186/s12916-024-03651-1
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