Archive for month: August, 2024

New Delhi: In line with the bioequivalence study report of Semaglutide Injection 2mg/1.5ml (1.34mg/ml) and 4mg/3ml (1.34mg/ml) (Synthetic Origin) presented by the drug major Dr Reddy’s Lab, the Subject Expert Committee (SEC) functional under the Central Drug Standard Control Organisation (CDSCO) has granted permission to conduct a Phase III clinical trial of Semaglutide Injection as per the protocol presented.

In addition, the expert panel opined that the firm submit the results for further deliberation.

This came after Dr. Reddy’s lab presented the bioequivalence study report and the Phase-III clinical trial protocol before the committee.

Semaglutide is a glucagon-like peptide 1 receptor agonist used to improve glycemic control in type 2 diabetes mellitus, treat obesity, and reduce the risk of major adverse cardiovascular events in selected adults.

GLP-1 is a physiological hormone that promotes glycemic control via several different mechanisms, including insulin secretion, slowing gastric emptying, and reducing postprandial glucagon secretion. The homeostasis of glucose is dependent on hormones such as insulin and amylin, which are secreted by the beta cells of the pancreas. Semaglutide is 94% similar to human GLP-1. Analogs of this hormone, such as semaglutide, stimulate the synthesis of insulin3 by stimulating pancreatic islet cells and reducing glucagon secretion. They directly bind with selectivity to the GLP-1 receptor, causing various beneficial downstream effects that reduce blood glucose in a glucose-dependent fashion.

Earlier, at 106 the SEC meeting held on 27.09.2023 and 29.09.2023, the firm had presented Bioequivalence protocol and Justification for Phase-III clinical trial waiver before the committee. Responding to this, the expert panel had stated that Phase-III clinical trial waiver can be considered based on the review of the bioequivalence study report by the SEC committee.

Now in line with the above, at the recent SEC meeting for Endocrinology and Metabolism held on July 24, 2024, the expert panel reviewed the bioequivalence study report along with the Phase-III clinical trial protocol of the Semaglutide Injection presented by the drug major Dr Reddy’s Lab.

After detailed deliberation, the committee considered the bioequivalence report and recommended the grant of permission to conduct a phase III clinical trial study as per the protocol presented and further stated to submit the results for further deliberation.

Also Read: Justify proposed dose and rationality: CDSCO Panel Tells Lupin on FDC Sacubitril plus Valsartan

On Saturday around noon, from Sangavi, a patient was brought
into the hospital by an ambulance and became disruptive and allegedly
intoxicated. The man began verbally and physically abusing the
staff of the hospital. He allegedly assaulted two nurses and a doctor at Aundh
District Hospital. Although, there is a police chowky, on the hospital premises
but no policeman was stationed at that chowky at the time of the incident.

Also Read:Mumbai: Drunk Patient attacks doctor with knife, slashes arm

In the past six months, this is the second time that
hospital staff have been subjected to such violence. The previous incident
involved an unknown visitor who damaged the hospital furniture, such as the
glass and table. Fortunately, the security staff prevented any major disaster
that day, said doctor Yempalay. He also mentioned the need for security and
police intervention in the hospital premises to ensure the safety of both staff
and patients.

A senior doctor speaking on the incident of violence has
expressed his concerns about the security of the hospital and has talked about
the need to increase police involvement to enhance the security system. He
mentioned, “The security at the hospital is inadequate, with only 21 security
guards. Seven security guards are there during the night shift which is
insufficient considering the huge hospital area and wards. There is no proper
lighting inside the hospital campus. The boundary wall of the hospital is
broken with huge trespassing,”

However, Mahesh Bansode Senior police Inspector at Sangavi
police station assured police officials are stationed at the police chowky
in the hospital. “However, if there are instances where they are not present
during their office hours, I will investigate the matter. We will ensure that
proper arrangements are made for policemen to be stationed at the
hospital,” he said.

As per the notification, candidates who are willing to take admission in undergraduate medical and dental courses must fill out the application form which is already available on the official website of NTR from 09 August 2024 at 02.00 PM to 16 August 2024 at 06.00 PM. 

Along with the registration, candidates also have to pay the registration fee, OC/BC candidates have to pay Rs. 2950/- (Rs. 2500/- + Rs. 450/- (GST @ 18%) Bank charges extra) and SC/ST candidates have to pay Rs. 23601- (Rs. 2000 + Rs. 360/- (GST @ 18%) Bank charges extra).

At the same time, if the candidates pay the registration fee after 06.00 PM on 16th August 2024, then an additional late fee will be charged from the candidates. Candidates can pay the late fee till 09.00 AM on 19th August 2024 till the display of the provisional merit list. After the addition of the late fee, the OC/BC candidates have to pay Rs. 22950/- and SC/ST candidates have to pay Rs. 22360/-. However, after the display of the Provisional Merit List, no further registrations will be allowed under any circumstances. The detailed registration with a late fee is as follows-

The eligible candidates have to submit their applications through online mode only along with uploading the scanned copies of all relevant original certificates and images of photo/signature.

Also, the same application will be considered for all the rounds of the counselling including MOP-UP round counselling and also for stray vacancies subject to fulfilment of eligibility criteria.

It is to be noted that due to technical reasons, candidates are informed that the availability of Online application will not be available from 07.00 PM on 16 August 2024 upto 09.00 PM on 18 August 2024. Hence, candidates who got registered and paid upto the above cutoff date but who could not upload the required scanned original documents can upload the same after 09.00 PM on 18 August 2024 and upto 20 August 2024 by 06.00 PM. Also, the application and Processing Fee including the Late Fee once paid will not be refunded or adjusted to a future date under any circumstances.

DOCUMENTS

Candidates also need to submit a few documents for Admission into undergraduate medical and Dental Courses for the seats available under Competent Authority Quota in the colleges affiliated to Dr NTR UHS, Vijayawada and also for MBBS seats in Sri Padmavathi Medical College for Women (under SVIMS), Tirupati for the Academic Year 2024-25. Following are the details to be submitted by the candidates-

1 NEET UG – 2024 Re-revised Rank Card.

2 Birth Certificate (SSC Marks Memo).

3 Qualifying Exam Certificate (Intermediate Marks Memo OR Equivalent — Grade Certificate not Accepted).

4 Study Certificates from 6th to 10th (If Single certificate upload the same for all years as a PDF file).

5 Study Certificates – Intermediate or equivalent for 2 Years Of Single certificate upload the same for arrears as PDF file).

6 Transfer Certificate (Intermediate / 10+2).

7 Caste Certificate.

8 Minority Certificate issued by Minority Welfare Officer (Muslim Only.

9 Income and Asset certificate for Economically Weaker Sections (EWS) valid for the year 2024-25 (Financial year 2023-24) issued by the Tahsildars concerned on or after 01.04.2024 pertaining to A.P – Non­Statewide Institutions and Tahsildars of AP & Telangana pertaining to Statewide Institutions for claiming reservation under EWS (candidates who are not covered under SC, ST & BC).

10 Parental Income Certificate/White Ration Card.

11 Person with Benchmark Disability (PwBD) Certificate.

12 NCC Certificates (If more than one certificate scan all into a single PDF file).

13 CAP Certificate (If more than one certificate scan all into a single PDF file) (If applicable)

i If retired personnel: 1. Children of Armed Forces Personnel (CAP) Certificate issued by the Zilla Sainik Welfare Officer. 2. Discharge Book (All pages). 3) Ex-Servicemen Identity Card issued by the Zilla Sainik Welfare Officer. 4) Pension Payment Order. 5) If any other priorities the proof of related documents. All certificates should be in a single PDF.

ii If Serving Personnel:

1. A Service Certificate issued by the Commanding Officer from the working Unit / Regiment duly mentioning the permanent home address declared by serving personnel at the time of enrolment in the Armed Forces.

2. If any other priorities the proof of related documents. All certificates should be in a single PDF.

14 Sports Certificate (If more than one certificate scan all into a single PDF file).

15 Police Martyr Children Certificate.

16 Anglo Indian Certificate.

17 Bharath Scouts and Guides Certificate.

18 Non-local candidates claiming 15 % of AP Unreserved seats.

19 Minimum 10 years Study Certificate of Student / either of parents, if studied in Andhra Pradesh only OR Minimum 10 years Residence Certificate (only Andhra Pradesh State) of either of parents OR Current employment Certificate of either of parents, if working in Andhra Pradesh only.

20 Aadhar Card.

21 Local status Certificate issued by MRO of AP (candidates migrated from Telangana to Andhra Pradesh.

22 Candidate’s Latest passport-size Photo.

23 Specimen Signature of the Candidate.

The application forms for Admission into undergraduate medical and Dental Courses are invited from the eligible General category (OC / EWS) candidates who have secured the 720/162 minimum cut-off score, Persons with Disability-General Category (OC/EWS) candidates who have secured the 161/144 minimum cut-off score and SC/ST/BC& Persons with Benchmark Disability of BC / SC/ ST Categories candidates who have secured the 161/127 minimum cut-off score in National Eligibility and Entrance Test- Undergraduate (NEET UG) 2024. Below are details of the minimum cutoff score obtained in NEET UG 2024

ELIGIBILITY

1 The candidate should be an Indian National or Person of Indian Origin (PIO) or Overseas Citizen of India (OCI) Card holder and should satisfy the Local or Non-local status in Andhra Pradesh. Provided that the candidates who got registered as Persons of Indian Origin (PIO) / Overseas Citizen of India (OCI) Cardholders on or after 04.03.2021 are eligible for admission only against any Non-Resident Indian seat or any supernumerary seat and will not be eligible for admission against any seat reserved exclusively for Indian Citizens.

2 The candidate should have passed Intermediate (10+2 pattern) or its equivalent examination with Physics, Chemistry, Biology (Botany, Zoology) / Biotechnology and English.

i OC candidates should obtain not less than 50% marks in Science subjects.

ii BC/SC/ST candidates should obtain not less than 40% marks in science subjects.

iii OC PwBD candidates should obtain not less than 45% marks in science subjects.

3 The candidate should complete 17 years of age as on 31-12-2024. The candidates who do not complete 17 years as on 31-12-2024 are not eligible for admission into MBBS and BDS Courses and they need not apply for the counseling.

4 The candidates who wish to claim seats under Anglo Indian, Sports & Games, CAP (Army), NCC, Persons with Disabilities (PWD), Bharath Scouts and Guides and Police Martyrs Children (PMC) also need to fulfil the eligibility criteria.

5 The candidates who claim admission under the Persons with Benchmark Disabilities (PwBD) category shall mention in the online application that they are applying under the PwD category and have to appear before the Medical Board, to be constituted by the Competent Authority and notified by the University for Eligibility under PwBD status along with a valid disability certificate issued not later than three months prior to submitting his /her application.

FEE STRUCTURE FOR MBBS COURSE

For the MBBS Course, all the government medical colleges have to pay a total of Rs. 15,000/-. Government Medical Colleges permitted from the academic year 2023-24 onwards will have to pay a total of Rs 32,15,000/-, Sri Padmavathi Medical College for Women (SVIMS), Tirupati have to pay a total of Rs 25,60,000 and Private Un-aided Minority and Non-Minority Medical Colleges will have to a total of Rs 52,96,500. Below are details of the fee structure for the MBBS Course-

FEE STRUCTURE FOR BDS COURSE

For the BDS Course, all government Dental colleges have to pay a total of Rs. 9,000 and Private Un-aided Minority and Non-Minority Dental Colleges will have to pay a total of Rs. 17,74,300. Below are details of the fee structure for the BDS Course-

To view the notification, click the link below