Red Cell Distribution Width and RDW/TSC Ratio may Effectively Predict Acute Pancreatitis Severity: Study

India: An observational cross-sectional
study demonstrates red
cell distribution width and RDW/TSC ratio are similar to the BISAP index as
predictors of severity in acute pancreatitis. The findings were published
online in The Journal of The Associations of Physicians of India
on July 01, 2024.

Acute pancreatitis occurs
when the pancreas becomes inflamed (swollen) for a short amount of time. It
involves acute pancreatic inflammation. The most prevalent causes of acute
pancreatitis include gallstones, alcohol consumption, and hypertriglyceridemia.
Symptoms may include fever, nausea, vomiting, rapid heartbeat, and a bloated or
painful abdomen. Chiranth Shivakumar, Post Graduate Resident, Vardhman Mahavir
Medical College and Safdarjung Hospital, Delhi, India, et.al conducted an
observational cross-sectional study to investigate red cell distribution width
and RDW/TSC ratio and are comparable to the BISAP index as predictors of
severity in acute pancreatitis.

For this purpose, the
research team conducted observational cross-sectional research of 85 patients
admitted to the medicine and surgical wards at VMMC and Safdarjung Hospital in
Delhi undertaken between December 2020 and June 2022. A history was taken, a
clinical examination was performed, and appropriate diagnostic tests were
ordered.

The study comprised 85
patients over the age of 18 who had been diagnosed with acute pancreatitis
using the new Atlanta classification. Then they divided into two groups. Those
with mild acute pancreatitis (MAP) and moderately severe/severe acute pancreatitis
AP (MSAP/SAP). Red cell distribution width was measured in all patients upon
admission and at the 24-hour mark.

The findings revealed
that:

  • Of the 85 AP patients, 55 were diagnosed with
    MAP, 17 with MSAP and 13 with SAP.
  • MSAP/SAP patients had significantly lower
    serum calcium levels compared to MAP patients.
  • Patients with MSAP/SAP had significantly
    higher modified Marshall (MM) scores, bedside index for severity in acute
    pancreatitis (BISAP) index, RDW at 0 and 24 hours, and RDW/total serum calcium
    (RDW/TSC) ratios compared to MAP.
  • The BISAP index was shown to be the most
    reliable predictor of severity, followed by MM. RDW/TSC also demonstrated good
    predictive value.
  • RDW/TSC outperformed RDW at admission and 24
    hours in terms of predicting AP severity. However, no single parameter has been
    established as an independent meaningful predictor of AP.

“Red
cell distribution width and RDW/TSC ratio are as good predictors of AP severity
as the BISAP index is. They provide a low-cost and easily accessible method of
forecasting AP severity at the time of admission, allowing for early
intervention”, researchers concluded.

Reference

Shivakumar, C., &
Kampani, G. (2024). Evaluation of Red Cell Distribution Width and Its Ratio to
Total Serum Calcium as Predictors of Severity in Acute Pancreatitis. The
Journal of the Association of Physicians of India, 72(7),
64–67. https://doi.org/10.59556/japi.72.0593

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Uterus Transplant Feasible with 70 Percent Success Rate and Live Births, Amid Frequent Adverse Events: JAMA

USA: In a landmark development, uterus transplants are emerging as a promising solution for women with absolute uterine-factor infertility (AUFI), a condition where the uterus is either absent or non-functional. This breakthrough offers new possibilities for women who previously had no options for carrying a pregnancy.

The study, published in JAMA, revealed that uterus transplantation proved feasible and led to at least one live birth following a successful allograft.

“In this study of 20 participants, 70% of uterus allografts were successful, and all recipients with successful transplants achieved at least one live birth. However, adverse events were prevalent, with medical and surgical risks impacting recipients and donors,” the researchers reported.

Uterus transplantation, a relatively new procedure in the field of reproductive medicine, involves surgically placing a healthy uterus from a donor into a recipient who lacks a functional uterus. The procedure has been gaining attention for its potential to enable women with AUFI to experience pregnancy and childbirth. The recent success of several high-profile cases has brought renewed hope to many individuals struggling with this condition.

Against the above background, Giuliano Testa, Baylor University Medical Center, Dallas, Texas, and colleagues aimed to determine whether a uterus transplant is safe and feasible and results in births of healthy infants.

A case series involving 20 participants with uterine-factor infertility and at least one functioning ovary was conducted at a major US tertiary care center between September 14, 2016, and August 23, 2019. These participants underwent uterus transplantation with grafts from 18 living donors and two deceased donors.

The transplants were surgically positioned in the orthotopic location with vascular connections to the external iliac vessels. Participants were given immunosuppressive therapy until the transplanted uterus was either removed following one or two live births or due to graft failure. The primary outcomes measured were the survival of the uterus graft and the occurrence of subsequent live births.

The following were the key findings of the study:

  • Of 20 participants (median age, 30 years; 2 Asian, 1 Black, and 16 White), 70% had a successful uterus allograft; all 14 recipients gave birth to at least one live-born infant. Eleven of 20 recipients had at least one complication.
  • Maternal or obstetrical complications occurred in 50% of the successful pregnancies, with the most common being gestational hypertension (14%), cervical insufficiency (14%), and preterm labor (14%).
  • Among the 16 live-born infants, there were no congenital malformations.
  • Four of 18 living donors had grade 3 complications.

The findings showed that uterus transplantation is technically feasible and resulted in a high rate of live births following successful graft survival. However, adverse events were frequent, with both medical and surgical risks impacting recipients and donors.

“To date, no congenital abnormalities or developmental delays have been reported in the children born from these procedures,” the researchers concluded.

Reference:

Testa G, McKenna GJ, Wall A, et al. Uterus Transplant in Women With Absolute Uterine-Factor Infertility. JAMA. Published online August 15, 2024. doi:10.1001/jama.2024.11679

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Saliva testing may improve screening of patients with heart failure, reveals study

Heart failure is a leading cause of death worldwide and is especially fatal for people who don’t have access to medical facilities. So, a team of researchers aims to bring heart failure screening from the lab to the home. Their point-of-care electrochemical biosensor prototype, which resembles a see-through lateral flow test for COVID-19, can measure levels of two biomarkers for heart failure in as little as 15 minutes from just a drop of saliva.

Trey Pittman, a graduate student at Colorado State University, will present his team’s research at the fall meeting of the American Chemical Society(ACS). ACS Fall 2024 is a hybrid meeting being held virtually and in person Aug. 18-22; it features about 10,000 presentations on a range of science topics.

“Our device would be ideal for people who are at high risk for heart failure but have limited access to a hospital or a centralized lab,” says Pittman. “Working on this project to address health disparities in rural and low-resource areas really hits home for me because I’m from Mississippi, which has one of the highest mortality rates from heart failure in the United States,” he shares.

Heart failure refers to weakened heart muscle that cannot pump enough oxygenated blood through the body. The current gold standard for heart failure screening is a blood test administered twice per year by a health care professional that measures levels of B-type natriuretic peptide (BNP), a protein that indicates the heart is working too hard.

However, new developments in point-of-care devices may level the proverbial health care playing field with simple, at-home saliva tests. Such a test for heart failure screening could be administered by an individual to check on the health condition every few weeks instead of every six months, suggests Pittman. So far, widespread use of portable saliva tests for heart health has been limited by complicated manufacturing techniques and lack of relevant data beyond the presence or absence of a single biomarker.

Pittman and colleagues took on these challenges and have promising results to share about an intuitive, low-cost biosensor prototype, which they call an electrochemical capillary-driven immunoassay (eCaDI). Charles Henry’s group at Colorado State University combined two of their previous innovations to create the handheld testing platform: a saliva microfluidic device and a biosensor for biomarker proteins Galectin-3 and S100A7. Collaborator Chamindie Punyadeera’s group at Griffith University in Australia, quantified levels of Galectin-3 and S100A7 in saliva that correlated to heart failure outcomes.

The heart failure eCaDI comprises five layers-like a club sandwich: Three layers of clear, flexible plastic held together with alternating layers of double-sided adhesive.

  • The top layer of plastic has tiny, drilled holes for loading the saliva sample.
  • The middle plastic layer has laser-cut channels with squares of blotting paper at the end that draw saliva from the loading site through the channels.
  • Wedged between the outer plastic layers are glass fiber reagent pads containing compounds that react with the saliva and measure Galectin-3 and S100A7 when an electrical current is applied to the device.
  • The bottom layer of plastic has carbon ink electrodes screen printed on its surface.
  • Two electrodes, powered by tiny, wired clamps from an external source called a potentiostat, drive the chemical reaction that happens on the reagent pads.

“The devices are very easy to assemble,” says Pittman. “In about 20 to 30 minutes, we can make five of them.” The eCaDI is single use, and the researchers estimate that each one costs about $3.00. The potentiostat, a small reusable power source, sells for about $20.

In demonstrations, the researchers spiked standardized human saliva samples with levels of the two biomarkers that would indicate heart failure. Their results showed that the eCaDI accurately detected the amounts of Galectin-3 and S100A7 in the saliva. “These demos are a first step towards a robust and non-invasive electrochemical sensor for heart failure biomarkers,” says Pittman. In their next step, the team will test eCaDIs at Griffith University in human subject research trials with healthy individuals and those with heart failure.

“This work may provide a starting point for new saliva testing platforms for other diseases,” Pittman shares. “It’s a technology that I think could end up helping a lot of people-especially the underserved-live longer, healthier lives.”

Reference:

Improving access to heart-failure screening with saliva, American Chemical Society, Meeting: ACS Fall 2024.

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Skin-only closure bests Bogota bag techniques for Temporary abdominal closure among patients with abdominal trauma: Study

Skin-only closure bests Bogota bag techniques for Temporary abdominal closure among patients with abdominal trauma suggests a new study published in the BMC Surgery.

Temporary abdominal closure (TAC) techniques are essential in managing open abdomen cases, particularly in damage control surgery. Skin-only closure (SC) and Bogota bag closure (BBC) are commonly used methods for TAC, but their comparative effectiveness in achieving primary fascial closure (PFC) remains unclear. The objective of this study was to evaluate the rates of PFC between patients undergoing SC and BBC techniques for TAC in peritonitis or abdominal trauma cases at a tertiary care hospital. A retrospective cross-sectional study was conducted at the Surgical A Unit of Hayatabad Medical Complex, Peshawar, from January 2022 to July 2023. Approval was obtained from the institutional review board, and patient consent was secured for data use. Patients undergoing temporary abdominal closure using either skin-only or Bogota bag techniques were included. Exclusions comprised patients younger than 15 or older than 75 years, those with multiple abdominal wall incisions, and those with prior abdominal surgeries. Data analysis utilized SPSS version 25. The study aimed to assess outcomes following damage control surgery, focusing on primary fascial closure rates and associated factors. Closure techniques (skin-only and Bogota bag) were chosen based on institutional protocols and clinical context. Indications for damage control surgery (DCS) included traumatic and non-traumatic emergencies. Intra-abdominal pressure (IAP) was measured using standardized methods. Patients were divided into SC and BBC groups for comparison. Criteria for reoperation and primary fascial closure were established, with timing and technique determined based on clinical assessment and multidisciplinary team collaboration. The decision to leave patients open during the index operation followed damage control surgery principles. Results: A total of 193 patients were included in this study, with 59.0% undergoing skin-only closure (SC) and 41.0% receiving Bogota bag closure (BBC). Patients exhibited similar demographic characteristics across cohorts, with a majority being male (73.1%) and experiencing acute abdomen of non-traumatic origin (58.0%). Among the reasons for leaving the abdomen open, severe intra-abdominal sepsis affected 51.3% of patients, while 42.0% experienced hemodynamic instability. Patients who received SC had significantly higher rates of primary fascial closure (PFC) compared to BBC (85.1% vs. 65.8%, p = 0.04), with lower rates of fascial dehiscence (1.7% vs. 7.6%, p = 0.052) and wound infections (p = 0.010). Multivariate regression analysis showed SC was associated with a higher likelihood of achieving PFC compared to BBC (adjusted OR = 1.7, 95% CI: 1.3–3.8, p < 0.05). In patients with peritonitis or abdominal trauma, SC demonstrated higher rates of PFC compared to BBC for TAC in our study population. However, further studies are warranted to validate these results and explore the long-term outcomes associated with different TAC techniques.

Reference:

Zahid, M.J., Hussain, M., Kumar, D. et al. A descriptive analysis of skin-only closure and Bogota bag techniques for achieving complete fascial closure in damage control abdominal surgery. BMC Surg 24, 192 (2024). https://doi.org/10.1186/s12893-024-02484-2

Keywords:

Skin-only, closure, bests, Bogota, bag, techniques, Temporary, abdominal, closure, among, patients, abdominal trauma, study, Zahid, M.J., Hussain, M., Kumar, D, Temporary abdominal closure, Skin-only closure, Bogota bag closure, Primary fascial closure,Peritonitis,Abdominal trauma

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Alkaline water non-pharmacological supplementary treatment for reducing pain and joint swelling in Gout: Study

Alkaline water non-pharmacological supplementary treatment for reducing pain and joint swelling in Gout suggests a study published in the Medicine (Baltimore).

Chronic gouty arthritis, a prevalent metabolic disorder, has prompted interest in the role of diet and lifestyle in its management. This study examines alkaline water as a non-pharmacological adjunct to traditional medicine, hypothesizing its positive effects on uric acid levels and gout symptoms. In this research, 400 chronic arthritis patients from Guangdong Hydropower Hospital (September 2021-September 2023) were randomly assigned to groups receiving varying concentrations of alkaline water alongside conventional Western medicine, or Western medicine alone. A 1-year follow-up involved assessments using visual analogue scales, joint swelling scores, functional assessment scales, and biochemical markers (serum uric acid, creatinine, urea nitrogen) for comprehensive evaluation. Results: Pain relief: High-concentration alkaline water significantly reduced VAS pain scores posttreatment (P < .05). Joint swelling: Greatest improvement observed in high-concentration group (P < .001). Daily activity capability: Notable enhancements in daily activity scores in experimental groups (P < .05). Range of joint motion: All groups showed significant improvement posttreatment (P < .05). Inflammatory markers: Experimental groups experienced a notable decrease in C-reactive protein, especially in the low concentration group (P < .001). Erythrocyte sedimentation rate decreases were marginal and not statistically significant (P > .05). Interleukin-1β and tumor necrosis factor-α levels significantly decreased, particularly in the low concentration group. Serum uric acid levels: Significant reduction in serum uric acid observed in all alkaline water groups (P < .05), contrasting with the control group. Alkaline water, particularly at high concentrations, effectively alleviated pain, reduced joint swelling, enhanced daily activities, and improved joint motion in chronic gouty arthritis treatment. It significantly reduced key inflammatory markers (C-reactive protein, interleukin-1β, tumor necrosis factor-α) and serum uric acid levels, suggesting its potential as a valuable adjunct in gout management. The limited impact on erythrocyte sedimentation rate warrants further investigation.

Reference:

Wu Y, Pang S, Guo J, Yang J, Ou R. Assessment of the efficacy of alkaline water in conjunction with conventional medication for the treatment of chronic gouty arthritis: A randomized controlled study. Medicine (Baltimore). 2024 Apr 5;103(14):e37589. doi: 10.1097/MD.0000000000037589. PMID: 38579090; PMCID: PMC10994428.

Keywords:

Alkaline water, non-pharmacological supplementary, treatment, reducing pain, joint swelling, Gout, studyl, Wu Y, Pang S, Guo J, Yang J, Ou R, ​​Medicine (Baltimore)

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Antibiotic prophylaxis not completely effective for post-extraction complications, States study

A new study published in the Journal of Public Health Dentistry found mild protective impact of antibiotic prophylaxis against post-extraction problems or subsequent medical care usage. For many dentists, extracting a tooth is a standard practice. Even though it’s a popular therapy, there is a chance that it can cause postoperative problems including discomfort, edema, and trismus and other issues. Due to the possibility of dry socket (DS) and surgical site infection (SSI), tooth extraction is considered a clean-contaminated procedure. Therefore, prophylactic antibiotics have long been used by dentists to avoid DS and SSI.

Amoxicillin, either by itself or in conjunction with clavulanic acid, is the most often prescribed antibiotic for preventing postoperative infection following extraction. Prophylactic antibiotic use is useful in preventing problems in high-risk patients and is recommended when there is an active infection during surgery. Therefore, this study by Jessina McGregor and colleagues assessed the relationship between the Veterans Affairs Healthcare System’s antibiotic prophylaxis and unfavorable outcomes after tooth extraction.

This study used a retrospective cohort analysis of individuals who had tooth extractions from 2015 to 2019 for this investigation. Prophylactic use of antibiotics was the primary exposure. Alveolar osteitis and surgical site infections were examples of post-extraction complications that occurred within seven days. Subsequent medical care for an oral problem that occurred within seven days was the secondary outcome. Antibiotic prophylactic was evaluated for its independent impact on each outcome using multivariable logistic regression models.

122,810 (31.8%) of the 385,880 dental extraction visits involved antibiotic prophylaxis. In all, 3387 (0.9%) people had a post-extraction oral problem, and 350 (0.09%) people sought medical attention for it within a week. Diabetes was a statistically significant (p = 0.01) impact modifier in multivariable analysis of the relationship between antibiotic prophylaxis and post-extraction complications.

Antibiotic prophylaxis was shown to be substantially related with a higher likelihood of post-extraction complications among visits from patients without diabetes, but no significant effect was seen when it came to visits from patients with diabetes. Also, prophylactic antibiotic use did not substantially correlate with post-extraction healthcare. Overall, the results indicate that it might be time to reevaluate the widespread application of antibiotics in such low-risk situations, given problems only occurred in 0.9% of instances. Antibiotics had no discernible impact on complications in diabetic individuals.

Source:

McGregor, J. C., Wilson, G. M., Gibson, G., Jurasic, M. M., Evans, C. T., & Suda, K. J. (2024). The effect of antibiotic premedication on postoperative complications following dental extractions. In Journal of Public Health Dentistry. Wiley. https://doi.org/10.1111/jphd.12634

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RG Kar Doctor rape-murder: Who is Dr Sandeep Ghosh? Former colleagues make host of allegations

Kolkata: The former principal of Kolkata’s RG Kar Medical College and Hospital, Dr Sandip Ghosh who has been making rounds at the doors of CBI for interrogation is at the centre of controversy after allegations of his being involved with several illegal activities came to light following the brutal rape and murder of a postgraduate student. 

The term ‘running Mafia-like operation’ to define the illegal activities allegedly run by the former principal during his tenure at the RG Kar Medical College and Hospital has become popular in the past few days after his former colleagues decided to come forward with accusations against him.  

Medical Dialogues recently reported that the Central Bureau of Investigation (CBI) officers questioned Sandip Ghosh, the former principal of Kar Medical College for the fourth consecutive day. Ghosh reached the CBI’s city office at CGO Complex on Monday morning.

Also read- Kolkata Doctor Death Case: Bengal SIT to investigate financial irregularities, CBI grills Former RG Kar Principal

According to the PTI report, Ghosh was asked to specify his role after getting the news of the death of the doctor, who he had contacted and why he made the parents wait for nearly three hours.

The ex-principal was also questioned who had ordered the renovation of the rooms near the seminar hall at the emergency building of the hospital after the incident.

Who is Sandip Ghosh?

Dr Sandip Ghosh, hailing from Bangaon, West Bengal, completed his higher secondary education at Bongaon High School in 1989. He pursued a career in medicine and graduated from RG Kar Medical College in 1994.

Ghosh rose to prominence when he was appointed principal of RG Kar Medical College in 2021, marking a return to his alma mater. Before this role, Ghosh served as vice-principal at Calcutta National Medical College. 

Previously, Dr Sandeep was transferred to the Murshidabad Medical College Hospital (MMCH) as a professor in the orthopaedic department, triggering controversy in the medical fraternity in 2023. He was transferred within 24 hours after being appointed as the principal of RG Kar Medical College & Hospital. It is worth mentioning that Ghosh was reappointed as the college principal of RG Kar Hospital for the second time in just over five months.

Despite his background as an orthopaedics professor and surgeon, he struggled to establish a strong reputation in the field. His tenure at RG Kar Medical College was marked by controversy, highlighting professional irregularities.

Allegations against him

In an interview with India Today TV, former colleagues and batchmates of Ghosh on condition of anonymity made several shocking allegations against him. 

A professor from another hospital in Bengal said that Ghosh ranked sixteenth during the interview process for the principal position. However, he secured the top spot becoming the principal of RG Kar Medical College. This has cast a shadow of mystery over the possibility of him becoming the principal despite having a low rank. 

As per the daily sources, Ghosh was accused of engaging in corrupt practices, including allegations of financial misconduct, claims of extorting money through illegal commissions and manipulating tenders during his time as principal of RG Kar Hospital. He has been also accused of redirecting corpses meant for post-mortem to unauthorised uses — a violation that struck at the core of medical ethics.

A former classmate of Ghosh, who spoke to India Today TV on condition of anonymity, “During our college years, he wasn’t known for any notorious behaviour. But power can change people, and it seems that might be the case with him.”

She also noted that “Ghosh’s first appointment was as the MSVP (Medical Superintendent cum Vice Principal) of National Medical College, hinting at a pattern of rapid, perhaps questionable, career advancements.”

The accusations against Ghosh did not end with financial corruption. Former colleagues have painted a picture of a principal who ran RG Kar Medical College like a personal fiefdom. 

Dr Akhtar Ali, a former deputy superintendent of the college, did not mince words in his assessment of Ghosh. “He is a very corrupt person. He used to fail students and takes 20 per cent commission. In the case of tenders, RG Kar used to extort money from every work of medical college and hospital and supply liquor to students in the guest house. He is like a mafia man, very powerful. I had earlier complained against him in 2023 but I was transferred after that,” Dr Ali added. 

Medical Dialogues had previously reported that amid ongoing protests by resident doctors over the rape and murder of a second-year postgraduate respiratory medicine medico at R G Kar Medical College Hospital, the principal Dr Sandip Ghosh resigned from his post a few days later. 

However, he was appointed as the principal of the Calcutta National Medical College & Hospital (CNMCH) through a notification issued by the West Bengal Health Department hours after resigning as the principal of state-run R G Kar Medical College & Hospital on Monday,

Speaking about Ghosh resigning, Dr Ali said, “His resignation (after the rape and murder) was an eyewash. He was appointed the principal of Calcutta National Medical College within eight hours.”

After the announcement of him taking charge as the principal of CNMCH, the medical students and doctors of the institute refused to accept him as the new principal of the institute and protested by locking the doors of the principal’s room.

After locking the principal’s room from outside on Monday evening, the medical students and junior doctors staged a dharna in front of the same room on Tuesday morning. They claimed that they would not allow Dr Ghosh to be their new principal.

Medical Dialogues also reported that a second-year postgraduate respiratory medicine medico was allegedly raped and murdered inside the campus after her body was found in the seminar hall of the R G Kar Medical College and Hospital. A preliminary autopsy report indicated sexual abuse before she was killed. As per the inquest report, there was bleeding from the doctor’s eyes and mouth, injury on the face and nails, bleeding from her genitals, and several other injury marks on different parts of her body. After this doctors across the country started a massive protest demanding justice for their colleague’s rape and murder.

Also read- West Bengal Orthopaedic Association bars former RG Kar Principal Dr Sandip Ghosh for indefinite period

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Female doctor assaulted by patient, kin at Sion Hospital

Mumbai: In a shocking incident, an on-duty female resident doctor at the civic-run Sion Hospital, Mumbai was allegedly assaulted and threatened by a patient and a group of 7-8 attendants who were in an intoxicated state.  

According to the police, the patient and his family started verbally abusing the on-duty doctor while she was examining the patient, who had arrived at the hospital with facial injuries. Initially, they started abusing the doctor but the situation quickly escalated to threats and physical assault against her. As a result, the doctor sustained injuries while defending herself.  

In response to the incident, the police have booked three persons, including two women and a man. Among them, two accused have been detained and both are women. 

Also read- Uttarakhand Horror: Nurse sexually assaulted, murdered on way home from Hospital

The incident took place on Sunday at around 3:45 PM in Ward 3 of Sion Hospital when a patient, who was intoxicated and had facial injuries came to the hospital. While the female doctor was cleaning blood from the ear of the patient, he began screaming in pain and shouting insults at the female doctor. 

Following this, the drunken relatives approached the doctor and began verbally abusing her later leading to physical assault. When the hospital staff called the security personnel, the patient and the relative fled away.  

This incident comes amid nationwide outrage and protests over the safety of doctors after a female postgraduate trainee doctor at RG Kar Hospital in Kolkata was allegedly raped and murdered on August 9.

Speaking to ANI, Dr Akshya More, General Secretary of Sion-Maharashtra Association of Resident Doctors (MARD) and BMC-MARD said, “The patient arrived in casualty after midnight in an intoxicated state with 7-8 relatives. He was involved in an assault before he came to the hospital, and had injury marks on his face. Owing to his injuries, he was given an ENT reference around 3:30 am. Our on-call resident doctor in the ENT department was a female.”

“Following a routine procedure, she undressed the wounds to examine them. That is when the patient started verbally abusing her. The relatives, instead of controlling the patient, started verbally abusing the resident doctor. Things escalated to physical assault very quickly,” said the doctor.

Adding further, he said, “Nurses intervened but by then the doctor had sustained abrasions on her hands. By the time security was called, the patient and the relatives had fled. Such incidents are very frequent and mostly go unreported but we could not let this one slide, especially after what happened in Kolkata.”

Based on the statement of the female doctor, Sion Police Station of Mumbai registered a case of misbehaviour and assault.

The Sion police registered a case under sections 115(2), 352, 3(5) and 3,4 of the BNS and the Maharashtra Medical Services and Medical Services Institutions (Prevention of Violent Acts and Loss or Damage to Property) Act, 2010.

In a statement concerning the incident, Sion Hospital said, “There has been an incidence of violence in Sion Hospital that occurred early this morning involving one of the on-call residents in the ward. A group of 5-6 intoxicated patient attendants threatened and attempted to physically assault her. She also sustained injuries while defending herself.” Terming the assault “alarming”, the statement said their doctors’ safety is “non-negotiable”. “This situation requires immediate attention and the implementation of strict security measures in all hospitals,” it added.

Medical Dialogues recently reported that the Union Ministry of Health and Family Welfare issued several directions to the Heads of all Central Government Hospitals/Institutes to ensure the safety and security of doctors and healthcare workers.

These measures, recommended by the Ministry, include installing sufficient numbers of High-resolution CCTV cameras, employing adequate number of well-trained security guards, setting up control rooms at the institutes, identification badges for staff, patients, visitors, restricting access to certain areas, identifying dark spots in the campus, well-secured duty rooms with basic amenities etc.

Further, the Ministry has recommended that lady health professionals should be deployed at night, preferably in more than one number and they should be escorted to premises while on duty and arrangements should be made for their transport or movement at night as well.

Also read- CCTV Cameras, Control Room, Security Guards: Health Ministry Issues measures for Central Hospitals, AIIMS, INIs to Ensure Safety of Doctors, Health Workers

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TN Health Releases Round 1 NEET Counselling Schedule for MBBS, BDS Admissions 2024, details

Tamil Nadu- Tamil Nadu (TN) Health has released the Round 1 counselling schedule for admission to MBBS and BDS degree courses in Tamil Nadu Government Medical and Dental Colleges for the academic year 2024-2025 session.

As per the schedule, the process of registration and payment and choice filling and locking will start tomorrow i.e. 21st August 2024 at 10:00 AM and will continue till 05:00 PM on 27th August 2024. After the completion of the registration and payment and choice filling and locking process, the processing of seat allotment will commence on 28 August 2024. Then on 29 August 2024, the provisional result will be declared and on 30 August 2024, the final result will be released.

After the declaration of the final result, candidates can download the provisional allotment order from 30 August 2024 to 05 September 2024 till 12:00 Noon. With this, the last date of joining is till 05 September 2024 till 05:00 P.M.

Below is the detailed schedule-

Also Read: TN Health Invites Applications for MBBS, BDS Courses for 2024-2025 Session: Check out details

SCHEDULE

S.NO

PROCESS

DATE & TIME FROM

DATE & TIME TO

1

Registration/ Payment and Choice Filling & Locking.

21 August 2024 10:00 A.M.

27 August 2024 05:00 P.M.

2

Processing of Seat Allotment.

28 August 2024

3

Provisional Result.

29 August 2024

4

Final Result.

30 August 2024

5

Downloading the Provisional Allotment Order.

30 August 2024

05 September 2024 12:00 NOON

6

Last Date of Joining

Till 05 September 2024 05:00 P.M.

Candidates who are willing to participate in the online choice filling for MBBS & BDS Degree Courses will have to remit a non-refundable Registration Fee of Rs.500/- for Government Quota and Rs.1000/- for Management Quota.

At the same time, candidates also have to pay a refundable Security Deposit of Rs.30,000/- for Government Quota in Medical & Dental Colleges & State Private Universities and Rs.1,00,000/- for Management Quota including Minority / NRI Category seats in self-financing Medical & Dental Colleges & State Private Universities.

Also Read: TN Health Releases Tentative Round 1 Counselling Schedule for MDS Admissions 2024, 387 Seats Available For Candidates

CHOICE FILLING

1 Candidates will have the option of choice filling for all the seats for which they have applied.

2 Candidates can edit their choices several times before locking, but once locked they will not be allowed to edit. Hence candidates are requested to check their choices and the order of preference before locking.

3 If the candidate does not lock his/her choices till the last date then their choices will be automatically locked.

4 The selection committee does not take responsibility for Connectivity error and Procedural error.

6 Admission to MBBS & BDS Degrees courses will be made by online counselling on the basis of rank by applying the rule of reservation.

7 Request for change of course (MBBS/BDS) or College, from one to another is not permitted after final locking.

INSTRUCTIONS FOR DOWNLOADING ALLOTMENT ORDER

1 The candidate if allotted a seat, (for MBBS seats in all colleges under all categories and BDS seats in Government Dental Colleges) he/she has to pay the Tuition Fee for downloading the Provisional allotment order through online via Debit Card / Credit Card/Net Banking.

2 The candidate if allotted a BDS seat in Self Financing Dental Colleges he/she has to pay the Tuition Fee at the time of admission to the colleges directly.

3 All candidates should make sure that they have a sufficient funds in their bank account with an expanded credit limit while remitting their Tuition Fee.

4 The allotted candidates should download their provisional allotment order and join the course in the concerned Medical College/Institution on or before the stipulated date and time as mentioned in the Provisional Allotment Order.

Also Read: TN Health asks FMGs seeking CRMI Training to submit documents, All Details Here

REPORTING TO ALLOTTED COLLEGE

1 The Certificate Verification will be done in the selected colleges itself.

2 The candidates should produce their original certificates in person at the time of joining in their selected Colleges along with a scanned copy of the original certificates for verification.

3 If the candidates do not report to the Head of the Institution to which they are allotted on or before the time and date specified, the selection and/or admission will be cancelled without any further notice.

4 The Candidate selected for admission should give a self-declaration form at the time of the reporting to the concerned College that he/she is liable for forfeiture of selection/admission if suppression of facts, or misinterpretation is found at any time during or after the admission to the course.

To view the schedule, click the link below

https://medicaldialogues.in/pdf_upload/tn-health-releases-round-1-counselling-schedule-for-mbbs-bds-admissions-2024-2025-248722.pdf

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USFDA issues EIR for Marksans Pharma Goa facility

Mumbai: Marksans Pharma has announced that the US Food and Drug Administration (USFDA) has issued an Establishment Inspection Report (EIR) for the manufacturing facility of the Company located at Plot No. L-82 & L-83, Verna Industrial estate, Verna, Goa.

The inspection has now been successfully closed by the USFDA. USFDA has determined that the inspection classification of this facility is “Voluntary Action Indicated” (VAI). VAI means objectionable conditions or practices were found, but the agency is not prepared to take or recommend any administrative or regulatory action.

Read also: Marksans Pharma arm gets UK MHRA marketing authorization for oral emergency contraceptive pill

The USFDA had inspected the facility from 9th April 2024 to 17th April 2024.

Read also: Marksans Pharma gets 5 inspectional observations from USFDA for Goa facility

Marksans Pharma Limited headquartered at Mumbai, India is
engaged in Research, Manufacturing & Marketing of generic pharmaceutical formulation in
the global markets. The company’s manufacturing facilities located in India, USA and UK are
approved by several leading regulatory agencies including USFDA, UKMHRA and
Australian TGA. The company’s product portfolio spreads over major therapeutic
segments of CVS, CNS, Anti-diabetic, Pain Management, Upper respiratory and
Gastroenterological. The company is marketing these products globally.

Read also: Marksans Pharma arm Relonchem bags UK MHRA marketing nod for oral solution to treat epilepsy

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