Acetaminophen shows promise in warding off acute respiratory distress syndrome, organ injury in patients with sepsis: Study

A National Institutes of Health (NIH)-supported clinical trial has found that intravenous acetaminophen reduced sepsis patients’ risk of having organ injury or developing acute respiratory distress syndrome, a serious condition that allows fluid to leak into the lungs. Sepsis is the body’s uncontrolled and extreme response to an infection. While the trial did not improve mortality rates in all patients with sepsis regardless of severity, the researchers found that acetaminophen gave the greatest benefit to the patients most at risk for organ damage. With the therapy, those patients needed less assisted ventilation and experienced a slight, though statistically insignificant, decrease in mortality. The study published in JAMA.

In sepsis, red blood cells become injured and die at abnormally high rates, releasing so called “cell-free hemoglobin” into the blood. The body becomes overwhelmed and can’t remove this excess hemoglobin which can lead to organ damage. Previous work from Lorraine Ware, M.D., professor of medicine, pulmonary and critical care at Vanderbilt University, Nashville, Tennessee, and the first author of the current study showed that acetaminophen, in addition to relieving pain and reducing fevers, had been shown to block the harmful effects of cell-free hemoglobin on the lungs, which are at major risk of injury during sepsis. Limited research had also suggested that acetaminophen might work better for patients with the most severe sepsis – those with higher levels of cell-free hemoglobin, which have been linked to a greater risk of developing acute respiratory distress syndrome and a higher risk of death.

Scientists note that identifying high levels of cell-free hemoglobin as a biomarker that could be tested when patients are first admitted to the hospital would be a breakthrough, because it could help quickly determine which patients with sepsis might benefit from acetaminophen therapy.

“One problem in critical care is the patients get sick so fast, that we do not normally have time to figure out which biomarkers help predict which therapy could give the best outcome,” said Michael Matthay, M.D., professor of medicine and anesthesia at the University of California, San Francisco, and the senior study author. “We hope that these findings will underscore the potential therapeutic value of using a biomarker to help successfully find a treatment that will work when patients need it the most.”

To test the therapeutic potential of acetaminophen more fully in a mid-stage clinical trial, researchers enrolled 447 adults with sepsis and respiratory or circulatory organ dysfunction at 40 U.S. academic hospitals from October 2021 to April 2023. Patients were randomized to receive either acetaminophen or a placebo intravenously every six hours for five days. The researchers then followed the patients for 28 days to see how they fared. They also completed a special analysis using data only from the patients with levels of cell-free hemoglobin above a certain threshold. The team’s primary interest overall was the number of patients who were able to stay alive with no organ support, such as mechanical ventilation or kidney failure treatment.

The researchers found that intravenous acetaminophen was safe for all the sepsis patients, with no difference in liver injury, low blood pressure, or other adverse events compared to the placebo group. Among secondary outcomes, they also found that organ injury was significantly lower in the acetaminophen group, as was the rate of acute respiratory distress syndrome onset within seven days of hospital admission.

When looking more closely at the patients with higher cell-free hemoglobin, the researchers found that just 8% of patients in the acetaminophen group needed assisted ventilation compared to 23% of patients in the placebo group. And after 28 days, 12% of patients in the acetaminophen group had died, compared to 21% in the placebo group, though this finding was not statistically significant.

“While the anticipated effects of acetaminophen therapy were not realized for all sepsis patients, this study shows that it still holds promise for the most critically ill” said James Kiley, Ph.D., director of the Division of Lung Diseases at the National Heart, Lung, and Blood Institute, part of NIH. “Though, more research is needed to uncover the mechanisms and validate these results.”

Ware said the results for the critically ill patients trended in a hopeful direction. She and Matthay plan to conduct a larger clinical trial, likely enrolling those patients primarily with higher cell-free hemoglobin levels.

Reference:

Ware LB, Files DC, Fowler A, et al. Acetaminophen for Prevention and Treatment of Organ Dysfunction in Critically Ill Patients With Sepsis: The ASTER Randomized Clinical Trial. JAMA. Published online May 19, 2024. doi:10.1001/jama.2024.8772.

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Superior metal artifact reduction of tin filtered low dose CT in imaging of lumbar spinal instrumentation compared to conventional computed tomography: study

Christoph Stern et al conducted a study to compare the image quality of low-dose CT (LD-CT) with tin filtration of the lumbar spine after metal implants to standard clinical CT, and to evaluate the potential for metal artifact and dose reduction.

CT protocols were optimized in a cadaver torso. Seventy-four prospectively included patients with metallic lumbar implants were scanned with both standard CT (120 kV) and tin-filtered LD-CT (Sn140kV). CT dose parameters and qualitative measures (1=worst,4=best) were compared. Quantitative measures included noise, signal-to-noise ratio (SNR), contrast-to-noise ratio (CNR), and the width and attenuation of the most prominent hypodense metal artifact. Standard CT and LD-CT were assessed for imaging findings.

Key findings of the study were:

• The body mass index was available in 64 of 74 patients and was mean 26.7±SD 4.2.

• A total number of 419 vertebra (the sacrum was counted as 1 vertebra) and of 451 pedicle screws were evaluated.

• Tin-filtered LD-CT was performed with 60% dose saving compared to standard CT (median effective dose 3.22 mSv (quartile 1–3: 2.73–3.49 mSv) versus 8.02 mSv (6.42–9.27 mSv; p<.001).

• Image quality of CT and tin-filtered low-dose CT was good with excellent depiction of anatomy, while image noise was lower for CT and artifacts were weaker for tin-filtered LD-CT.

• Quantitative measures also revealed increased noise for tin-filtered low-dose CT (41.5HU), lower SNR (2) and CNR (0.6) compared to CT (32HU,3.55,1.03, respectively) (all p<.001).

• Tin-filtered LD-CT performed superior regarding the width and attenuation of hypodense metal artifacts (2.9 mm and -767.5HU for LD-CT vs. 4.1 mm and -937HU for CT; all p <001).

• No difference between methods was observed in detection of imaging findings.

The authors concluded – “In summary, with tin prefiltration and a low-dose protocol, 60% dose saving was achieved for CT of the lumbar spine with metal implants without compromise in detection of pathology and surgery related complications. Furthermore, reduction of metal artifacts was superior for the tin-filtered low-dose CT compared to the clinical standard protocol without tin prefiltration.”

Further reading:

Superior metal artifact reduction of tin filtered low dose CT in imaging of lumbar spinal instrumentation compared to conventional computed tomography

Christoph Stern et al

Skeletal Radiology (2024) 53:665–673

https://doi.org/10.1007/s00256-023-04467-5

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Study reveals Long-Term Impact of Adverse Pregnancy Outcomes on Cardiovascular Health

Recent research paper aimed to investigate the potential association between adverse pregnancy outcomes and the predicted 30-year risk of atherosclerotic cardiovascular disease (CVD), including coronary artery disease and stroke. The study was a secondary analysis of the prospective Nulliparous Pregnancy Outcomes Study–Monitoring Mothers-to-Be Heart Health Study longitudinal cohort. The exposures were adverse pregnancy outcomes during the first pregnancy, including gestational diabetes mellitus (GDM), hypertensive disorder of pregnancy, preterm birth, and small- and large-for-gestational-age (SGA, LGA) birth weight. The outcome was the 30-year risk of atherosclerotic CVD predicted with the Framingham Risk Score assessed at 2–7 years after delivery. The study included 4,273 individuals and found that those who experienced GDM, hypertensive disorder of pregnancy, and preterm birth were more likely to have a higher absolute risk and a high predicted risk of atherosclerotic CVD. A greater number of adverse pregnancy outcomes within the first birth was associated with progressively greater risks.

The study was part of the Nulliparous Pregnancy Outcomes Study–Monitoring Mothers-to-Be Heart Health Study and the follow-up nuMoM2b-HHS, which aimed to better define the relationships between adverse pregnancy outcomes and maternal cardiovascular health. Adverse pregnancy outcomes were defined as GDM, hypertensive disorder of pregnancy, preterm birth, and abnormal birth weight (SGA and LGA). The predicted 30-year risk of atherosclerotic CVD was assessed using the Framingham Risk Score and measured continuously and categorically. The study found that the cumulative number of adverse pregnancy outcomes was associated with a higher risk of atherosclerotic CVD. In addition, the study revealed that individuals with a higher BMI, those with chronic hypertension, and those who reported smoking were more likely to experience an adverse pregnancy outcome.

Study Limitations

Despite the significant findings, the study had limitations. It did not assess the association of adverse pregnancy outcome severity with atherosclerotic CVD risk, and the cohort excluded individuals with pregestational diabetes. However, the study’s strengths included leveraging well-characterized adverse pregnancy outcomes through medical record abstraction and rigorous adjudication. This resulted in a geographically and racially diverse population, allowing for the assessment of a dose–response relationship between the number of adverse pregnancy outcomes and the degree of atherosclerotic CVD risk.

Conclusion

In conclusion, the study’s findings indicated that individuals who experienced adverse pregnancy outcomes in their first birth were more likely to have a higher predicted 30-year risk of atherosclerotic CVD. These findings underscore the importance of continued risk assessment and engagement in preventive care after an adverse pregnancy outcome to reduce atherosclerotic CVD risk and improve maternal health.

Key Points –

– The research aimed to investigate the association between adverse pregnancy outcomes and the predicted 30-year risk of atherosclerotic cardiovascular disease (CVD), including coronary artery disease and stroke. The study included 4,273 individuals and found that those who experienced gestational diabetes mellitus (GDM), hypertensive disorder of pregnancy, and preterm birth were more likely to have a higher absolute risk and a high predicted risk of atherosclerotic CVD. A greater number of adverse pregnancy outcomes within the first birth was associated with progressively greater risks.

– The study was part of the Nulliparous Pregnancy Outcomes Study–Monitoring Mothers-to-Be Heart Health Study and the follow-up nuMoM2b-HHS. Adverse pregnancy outcomes were defined as GDM, hypertensive disorder of pregnancy, preterm birth, and abnormal birth weight (SGA and LGA). The study found that the cumulative number of adverse pregnancy outcomes was associated with a higher risk of atherosclerotic CVD. Individuals with a higher BMI, chronic hypertension, and those who reported smoking were more likely to experience an adverse pregnancy outcome.

Reference –

Venkatesh KK, Khan SS, Yee LM, Wu J, McNeil R, Greenland P, Chung JH, Levine LD, Simhan HN, Catov J, Scifres C, Reddy UM, Pemberton VL, Saade G, Bairey Merz CN, Grobman WA; Nulliparous Pregnancy Outcomes Study: Monitoring Mothers-to-Be (nuMoM2b), and nuMoM2b–Heart Health Study (HHS) Investigators. Adverse Pregnancy Outcomes and Predicted 30-Year Risk of Maternal Cardiovascular Disease 2-7 Years After Delivery. Obstet Gynecol. 2024 Jun 1;143(6):775-784. doi: 10.1097/AOG.0000000000005569. Epub 2024 Apr 5. PMID: 38574364; PMCID: PMC11098696

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Baby Born with 90 percent Locomotor Disability: Hospital, Doctor slapped Rs 50 lakh compensation for failure in detecting anomaly during gestation period

Thiruvananthapuram: The Kerala State Consumer Disputes Redressal Commission recently directed Malappuram-based hospital and its doctor to pay Rs 50 lakh as compensation to a woman who gave birth to a child with 90% locomotor disability. It was alleged that neither the hospital nor the doctor had even given her any indication regarding the abnormality of the child before delivery despite repeated scans. 

While considering the matter, the State Consumer Court had set up a Medical Board, which had opined that the doctor had not exercised reasonable skill while conducting the ultra-sound scan. The Board had opined that if the doctor had exercised reasonable skill, the deformity could have been detected at the scan done when the gestation age was sixteen weeks.

Considering the Medical Board’s opinion, the SCDRC directed the hospital and doctor to pay Rs 50 Lakh as compensation and Rs 50,000 as cost of litigation to the complainant.

The case goes back to the year 2007 when the patient was under the observation and treatment of Dr. G. Menon for her pregnancy-related complications. Earlier she had delivered two babies through caesarean surgeries but both the babies were born with ‘down syndrome’ and the babies had died within a few days after being born. After being advised by various doctors about the risks of the third delivery, the complainant started taking advice and treatment from the treating doctor’s hospital to avoid such complications.

As suggested by the doctor, the patient and her husband underwent ‘Chromosonal Analysis’, which showed that there were no abnormalities. Therefore, considering the doctor’s advice, she became pregnant and after her conception, at each stage, the complainant made inquiries regarding the status of the foetus to ensure that abnormal foetus could be aborted at the earliest stage. She submitted that this was her last chance to undergo a caesarean surgery for delivery as both of her earlier deliveries were through caesarean sections. 

She underwent scanning during the tenth, sixteenth, and twenty-first weeks of her pregnancy at the treating hospital and the results were stated to be normal with no abnormalities being detected. On 09.02.2007, the doctor and his team conducted a Chromosome Analysis for the foetus and no abnormalities were detected.

There were no abnormalities even in the scannings taken in the twenty-sixth, thirtieth, and thirty-fifth week of pregnancy. Finally, the complainant opted for a caesarean operation to ensure a safe delivery as no complication or abnormality was detected by the doctor and the hospital or communicated to her.

However, the patient was shocked to find out that a baby boy she delivered had abnormally formed limbs. She claimed that the said consequence was only due to the gross negligence and deficiency in service of the doctors who treated her. It was alleged that the hospital and doctor had promised the patient that she would be adequately compensated by the payment of a lump sum amount or an annual payment if the child survived one year. However, that promise was allegedly not honoured by the hospital and the doctor. 

As per the complainant, the child survived for more than one year and required constant attention and care of an attendant. She claimed that had the deformity of the foetus been detected at an early stage, the complainant could have undergone an abortion. Therefore, filing the consumer complaint, the patient prayed for Rs 50 lakh compensation for deficiency in service and for the mental agony and suffering.

On the other hand, the hospital and the doctor submitted that they had been referred to the doctor as an expert to rule out the chances of Down syndrome by advanced medical and scientific methods. Accordingly, the doctor advised the complainant and her husband for Karyotype as an accepted method to rule out chromosomal problems that can cause recurrent Down syndrome. He referred to the other scanning and tests that were conducted to rule out the possibilities of abnormalities and submitted that all the results were found to be normal. 

It was also submitted that even though the complainant was asked for scans within 18 to 22 weeks of gestation to rule out any abnormalities other than Down syndrome, the complainant did not turn up for the same and expressed that she only wanted to rule out the chances of down syndrome since believed that her previous two babies were lost due to down syndrome. They claimed that the treatment given to the complainant was as per the standard medical practice.

During the pendency of the complaint, the State Consumer Court had set up a Medical Board on 18.11.2009 and the Board examined the medical records of the complainant as well as the child born to her. The panel noted that the child’s right forearm was absent and the right hand had a rudimentary nodule over the right medical aspect of the right stump. The left forearm was missing and the right leg appeared short with talipes deformity of the rudimentary food. The child’s left leg is marked by short with a rudimentary foot.

Taking note of these deformities, the Panel noted except for the limb anomalies his growth and mental development were normal. Therefore, the Committee opined that “these anomalies should have been detected by the ultra sound scan done at sixteen and twenty two weeks gestation. The gross limb anomalies like absence of forearm and legs should have been detected by the ultra sound scans, if Dr.*** Menon had exercised reasonable skill; especially since the liquor volume was normal.”

Referring to the Panel’s report, the Consumer Court noted,

“The above conclusion of the Medical Board categorically finds that the 2nd opposite party had not exercised reasonable skill while conducting the ultra sound scan. Had reasonable skill been exercised by the 2nd opposite party, the deformity could have been detected at the scan done when the gestation age was sixteen weeks.”

Accepting the Medical Board’s opinion, the Consumer Court observed,

“Since the Medical Board had actually examined the child and the medical records of the case and concluded definitely that the deformities could have been detected at an early date, had reasonable skill been exercised by the 2nd opposite party while conducting the ultra sound scan, the actual causes of the deformities are not necessary to be enquired into, any further. The Medical Board having been constituted with eminent persons holding responsible positions and having expertise in their specialised fields were the best persons capable of evaluating the treatment provided, assessing whether reasonable skill had been exercised and identifying the lapses that were alleged to have occurred. Since they have categorically concluded that the deformities could have been detected, had the 2nd opposite party exercised reasonable skill while conducting the ultra sound scan, we accept the said conclusion.”

Therefore, the Commission concluded that it was due to the omission on the part of the doctor to exercise reasonable skill while conducting the ultrasound scan of the complainant that the deformities of the child born to her were not detected sufficiently early. Due to this, a deformed child suffering from ninety per cent loco-motor disability was born to the complainant, completely upsetting her normal life.

“Since the child requires her constant attention and care, she has been prevented from taking up any employment. Her desire to have a normal healthy child was also shattered. The magnitude of the damage to her life is manifold and therefore she seeks compensation. The difficulty of looking after a child like that of the complainant, born with a severe loco-motor disability estimated at ninety percent cannot be overstated, as contended by the counsel for the complainant. The child would require assistance even for answering its calls of nature. As it grows up, the difficulties would only increase many fold. The prospect of educating the child or even looking after the child properly would be impossible without the assistance of a caring, trained and responsible person. The services of such a person would be difficult to obtain and would certainly entail substantial expenditure. The burden of looking after the child has been cast on the complainant in spite of all the efforts taken by her to obtain medical feedback with respect to the health condition of the child, solely because of the deficiency in service on the part of the opposite parties. Since the 2nd opposite party was at that time working with the 1st opposite party hospital, the 1st opposite party is also vicariously liable for the losses caused to the complainant,” noted the Commission.

The Commission examined the photographs of the child and noted that the child requires constant attention and care. Considering the difficulties in bringing up a child suffering from such deformities, the Commission allowed the compensation sought in full.

It directed the hospital and the doctor to pay Rs 40 lakh as compensation for deficiency in service and negligence with interest @8% per annum from 13.07.2009, Rs 10 lakh for mental agony and sufferings caused to the complainant with interest @8% per annum and Rs 50,000 as litigation cost to the complainant.

“Both the opposite parties are directed jointly and severally pay to the complainant an amount of Rs.40,00,000/-(Rupees Forty Lakhs only) as compensation for the deficiency in service and negligence with interest thereon @8% per annum from 13.07.2009 the date of filing the complaint. Both the opposite parties are held jointly and severally liable to compensate the complainant for the mental agony and sufferings caused to her by paying an amount of Rs.10,00,000/-(Rupees Ten Lakhs only) with interest thereon @8% per annum from the date of filing the complaint. The opposite parties are directed jointly and severally pay a further amount of Rs.50,000/- (Rupees Fifty Thousand only) as the costs of litigation to the complainant,” the Commission ordered.

To read the order, click on the link below:

https://medicaldialogues.in/pdf_upload/rs-50-lakh-compensation-239833.pdf

Also Read: Ovary Removed Sans Consent, Mop pad left inside Abdomen: TN Private Hospital Doctors Told to Pay Rs 25 Lakh Compensation

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Conduct BE study: CDSCO Panel Tells Sun Pharma Labs on COPD drug Umeclidinium powder for inhalation

New Delhi: In line with the proposal to manufacture and market Umeclidinium powder for inhalation 62.5mcg, the Subject Expert Committee (SEC) functional under the Central Drug Standard Control Organisation (CDSCO) has opined the drug major Sun Pharma Labs to conduct bioequivalence study with pharmacokinetic endpoints for which firm should submit bioequivalence protocol to CDSCO for further review by the committee.

This came after Sun Pharma Labs presented its proposal for a grant of manufacture and marketing of Umeclidinium powder for inhalation 62.5mcg along with justification for waiver of Phase-III clinical trial and bioequivalence study before the committee.

The firm has informed that the proposed drug Umeclidinium powder for inhalation 62.5mcg is already in the USA, UK, EU, Australia, and Canada for Chronic obstructive pulmonary disease.

The firm also informed that Umeclidinium is approved in India as part of the fixed-dose combination (FDC) of fluticasone furoate, Umeclidinium and vilanterol (100mcg + 62.5mcg+25mcg) for the same indication.

Umeclidinium is a long-acting muscarinic antagonist (LAMA) used as a maintenance treatment for symptoms of chronic obstructive pulmonary disease (COPD). COPD is a progressive obstructive lung disease characterized by shortness of breath, cough, sputum production, and chronically poor airflow with a forced expiratory volume in 1 second (FEV1) of less than 80%.

Umeclidinium blocks muscarinic M3 receptors. M3 receptors in the lungs mediate bronchoconstriction, so blockade of these receptors leads to bronchodilation.

This medicine will not relieve a COPD attack that has already started. Inhaled umeclidinium is a long-acting bronchodilator. This medicine is breathed in through the mouth to open up the bronchial tubes (air passages) in the lungs.

At the recent SEC meeting for Pulmonary held on 21st May 2024, the expert panel reviewed the proposal for a grant of manufacture and marketing of Umeclidinium powder for inhalation 62.5mcg along with justification for waiver of phase-III clinical trial and bioequivalence study.
After detailed deliberation, the committee opined to conduct a bioequivalence study with pharmacokinetic endpoints for which the firm should submit the bioequivalence protocol to CDSCO for further review by the committee.

Also Read:AstraZeneca Pharma India Gets CDSCO Panel Nod To Import, Market Eculizumab for Atypical hemolytic uremic syndrome

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Delhi Neonatal Hospital fire: Court sends two doctors to 14-day judicial custody

New Delhi: Delhi Lieutenant Governor V K Saxena has suspended Health Minister Saurabh Bharadwaj’s Officer on Special Duty (OSD), R.N. Das, for his alleged involvement in the irregular and illegal registration of private nursing homes, including the one in Vivek Vihar where six newborns were killed in a fire, officials said.

A metropolitan court here on Thursday sent to 14 days judicial custody the owner and on-duty doctor of the private hospital where a blaze on May 25 killed seven newborns and injured five.

Chief Metropolitan Magistrate Vidhi Gupta Anand sent Dr Naveen Khichi, the hospital’s owner and Dr Aaksh, who was on duty at the time of the fire late last Saturday, to judicial custody.

According to a PTI report, Meanwhile, the doctor has filed a bail plea which will be heard on June 3.

Also Read:Delhi Neonatal Hospital Fire: 30 minutes delay in making distress call, LG Saxena orders ACB probe

In the order issued on Wednesday, the Vigilance Directorate said, “The Hon’ble Lt. Governor, Delhi, in the exercise of the powers conferred by sub-rule (1) of Rule-10 of the CCS (CCA) Rules, 1965, hereby, places the said Dr R.N. Das, Officer on Special Duty (OSD) to Hon’ble Minister (Health), GNCTD, under suspension with immediate effect.” In a letter to Anti Corruption Branch(ACB) the directorate also said that Lt Governor, has directed the agency to undertake an “urgent comprehensive enquiry” into the registration of Nursing Homes under Delhi Nursing Home Registration Act, 1953 and Rules and submit an action taken report by June 5, news agency PTI reported.

A massive fire broke out on Saturday night at Baby Care New Born Child Hospital in east Delhi’s Vivek Vihar that was allegedly operating illegally with an “expired” licence and without any clearance from the fire department. 

Medical Dialogues team had earlier reported that In a tragic incident, seven newborns died and five got injured after a baby care centre in Delhi’s Vivek Vihar caught fire. 

A case has been registered at Vivek Vihar police station under IPC sections 336 (act endangering life and personal safety of others), 304A (causing death by negligence), 304 (culpable homicide not amounting to murder) and 308 (attempt to commit culpable homicide).

The two were arrested on Sunday and were remanded in police custody on May 27.

Also Read:7 Newborns dead, 5 Injured: What Went Wrong in Delhi’s Neonatal Hospital that Caught Fire?

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Dentists Tackle Tobacco: Key Players in Smoking Cessation Ft Dr. Vikrant Mohanty

Every year 31st May is marked as World No Tobacco Day. This yearly celebration informs the public on the dangers of using tobacco, the business practices of tobacco companies, what organizations are doing to fight the tobacco epidemic, and what people around the world can do to claim their right to health and healthy living and to protect future generations.
In this video, Dr. Vikrant Mohanty, Professor And Head Of Department, Department Of Public Health Dentistry, Maulana Azad Institute Of Dental Sciences, Delhi, discusses the role of dentists in tobacco cessation.
He talked about the following:
1. Impact of tobacco use on oral health
2. Dentists and tobacco cessation counseling
3. Strategies to help patients quit smoking
4. Effectiveness of Nicotine Replacement Therapies
5. Barriers faced by dentists in tobacco cessation counseling

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NMC task force conducts meeting with stakeholders on issues of mental health of medical students

The National Task Force, constituted by the Anti-Ragging Cell of the National Medical Commission (NMC), conducted its meeting today with the stakeholders to discuss the issues related to the mental health and well-being of medical students.
The Chairman of the Apex Medical Regulator Dr. B.N. Gangadhar and other members including the President of the Undergraduate Medical Education Board (UGMEB), Dr. Aruna V Vanikar, the President of the Postgraduate Medical Education Board (PGMEB) Dr. Vijay Oza, member of NMC Ethics Board, Dr. Yogender Malik, NMC Secretary Dr. B. Srinivas and Deputy Secretary Dr. Aujender Singh. The Chairman of the National Task Force, Dr. B.M Suresh, Professor of the Department of Psychiatry, NIMHANS, and a representative from the University Grants Association (UGC), Alka Tomar were also present in the meeting.
For more information click on the link below:

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NMC notifies final decision on 143 applications from 28 medical colleges to start new PG medical courses, seats increment

Through a recent notice, the Medical Assessment and Rating Board (MARB) of the National Medical Commission (NMC) has notified its final decision on 143 applications received from 28 medical institutes for starting new postgraduate medical courses and increasing the PG medical seats in the existing courses for the academic year 2024-2025.
Among these 143 applications, 107 applications were for the starting of new PG medical courses and 36 applications for an increase of seats in PG medical courses.
For more information click on the link below:

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