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Mumbai: Jaslok Hospital and Research Centre proudly announces a significant medical milestone in the diagnosis and treatment of Primary Bilateral Trigeminal Neuralgia (PBTN).
A 56-year-old housewife from the interiors of Maharashtra, suffering from this debilitating condition, has experienced complete pain relief following Bilateral Micro Vascular Decompression (MVD), marking a major advancement in neurosurgery and the first in India.
The patient, with a five-year history of severe, shock-like pain on both sides of her face, endured excruciating episodes that lasted several minutes and were triggered by everyday activities such as talking, eating, brushing her teeth, and even exposure to a cool breeze. Despite various medical treatments, she found no relief because the disease was not diagnosed. The excruciating pain made it difficult to perform basic household duties to an extent that it led to the development of suicidal thoughts.
Also Read:77-year-old Zambian man with triple cancers gets new lease of life at Jaslok Hospital
Referred to Jaslok Hospital in October 2023, Dr Raghvendra Ramdasi diagnosed her with Bilateral Primary Trigeminal Neuralgia. An MRI scan revealed vascular loops compressing her trigeminal nerves (fifth cranial nerve) on both sides.
Primary Bilateral Trigeminal Neuralgia is an extremely rare, with an incidence ranging from 0.6% to 5.9%. To date, only about 24 cases have been reported in the English medical literature, with none from India. This case marks the first reported instance in India where Bilateral MVD was performed, resulting in complete pain relief.
The trigeminal nerve, or fifth cranial nerve, supplies sensation to the face through three divisions. Trigeminal Neuralgia is a chronic pain disorder characterized by sudden, severe facial pain, often described as electric shock-like. Typically unilateral, the condition affects one or more divisions of the trigeminal nerve. In about 85% of cases, the cause is a vascular loop compressing the nerve at its root entry zone.
While medications such as Carbamazepine, Gabapentin, Lamotrigine, and Topiramate can offer relief, Micro Vascular Decompression (MVD) remains the gold standard treatment. This surgical procedure involves placing a Teflon sponge between the nerve and the compressing vessel.
Under the leadership of Dr Raghvendra Ramdasi, Consultant Neurosurgery at Jaslok Hospital, the medical team including Dr Poornima Shah, Consultant Neurophysiology, Dr Rajani Prajish, Consultant Anaesthesiology, Dr Savi Kapila, Consultant Anaesthesiology performed Bilateral Micro Vascular Decompression, initially operating on the more severe left side, followed by the right side a week later. Post-surgery, the patient experienced complete pain relief, significantly improving her quality of life. Six months later, she continues to live pain-free, able to resume normal activities without fear of pain attacks.
Dr Raghvendra Ramdasi, Neurosurgeon at Jaslok Hospital, “Bilateral Trigeminal Neuralgia is often described as one of the most painful conditions a person can experience. This rare case was accurately diagnosed and hence treated with precision with Bilateral Micro Vascular Decompression, the first in India. Seeing our patient regain her quality of life after 5 years and live pain-free is the greatest reward. This case highlights the importance of expert diagnosis and the need for specialized care in managing rare conditions.”
Kiran Awasthi with joy mentioned “Dr Ramdasi is has brought me from the doors of death. I was about to commit suicide as the pain was unbearable. He has gifted me a new life”
Dr Paresh Doshi, Director of Neurosurgery, Functional neurosurgery and Stereotactic Neurosurgery, at Jaslok Hosptial, “The diagnosis of Primary Bilateral Trigeminal Neuralgia (PBTN) is a rare occurrence and the successful completion of bilateral MVD at Jaslok Hospital is definitely a commendable achievement. While the surgical procedure of Bilateral Micro Vascular Decompression (MVD)is well-established, Bilateral Decompressive Surgery is uncommon. ”
Dr Milind Khadke, Director Medical Services of Jaslok Hospital: “The successful treatment of Primary Bilateral Trigeminal Neuralgia with Bilateral Micro Vascular Decompression, the first in India, is a monumental achievement for Jaslok Hospital. We are proud of our team’s dedication to be vigilant in diagnosis of rare cases and thereby delivering life-changing results. I am delighted to see our patient walking out pain-free and continuing the same now for months”
Also Read:8-year-old Yemeni boy undergoes rare thyroid cancer surgery at Jaslok Hospital
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New Delhi- The Medical Counselling Committee (MCC) has informed through a notice that from this year, counselling for Priority III, IV and V candidates in Armed Forces Medical Services (AFMS) PG teaching institutes will be conducted by the MCC of DGHS. In addition, FAQs for candidates desirous of participating in AFMS MDS counselling 2024 have also been released.
AFMS conducts postgraduate training in AFMS PG Teaching Institutes primarily for the in-service medical and dental officers of the AFMS to fulfil the specialist requirements. Surplus seats, if any, are offered to other eligible candidates as per priority system sanctioned by the Govt of India. The civilian doctors who get admission in postgraduate courses (MD/MS/DNB/MDS) at any AFMS institution shall be liable to serve as Short Service Commissioned Officers (SSC) for 05 years in AFMS.
As sanctioned by the Govt of India, after fulfilling the AFMS requirements, the remaining seats in the AFMS PG Teaching Institutes, if any, are made available to other eligible candidates as per the priority system outlined below-
1 Priority-I: AFMS Officers detailed on Advance Specialist Course/ PG courses.
2 Priority-II: Foreign students sponsored by Government and AFMS officers granted Study Leave.
3 Priority-III: Medical Officers sponsored by Para Military Organization/ other Govt. of India organization.
4 Priority-IV: Ex-SSC AFMS Officers within 03 years of their release from service.
5 Priority-V: Civilian candidates.
As per the notice, the counselling for Priority-I & II candidates will be conducted by O/o DGAFMS and counselling of Priority-III, IV & V candidates will be conducted by MCC. Candidates of all priorities are advised to register themselves on the MCC portal for counselling as per the schedule. More information in this regard will be available on the MCC official website and the AFMS website. Seat allotment during counselling by MCC is provisional and subject to fulfilment of all eligibility criteria as mentioned in the ‘Information Bulletin for PG Courses in AFMS Institutions through NEET PG-2024 and NEET MDS-2024’. AFMS reserves the right to deny admission to any candidate who is found to be ineligible as per the eligibility criteria enumerated in the Information Bulletin mentioned. The redressal of disputes, if any, shall only be through civil courts having jurisdiction of New Delhi alone.
The last date for the sponsorship certificate of Priority-III candidates & applications of Priority-IV candidates for MDS seats in AFMS Institutions to reach the O/o DGAFMS is 05 July 2024.
MDS seats available for Priority-III, IV & V candidates (MDS) in AFMS institutions for academic session 2024-2027 are as under-
|
S.NO |
SPECIALITY |
INSTITUTION |
SEATS AVAILABLE FOR PRIORITY-III, IV & V |
|
1 |
Periodontology. |
AFMC, Pune |
Below are the FAQs-
Q1 Who can register on MCC for counselling for admission into AFMS PG Teaching Institutes?
A Admission into the Post Graduate courses (MD/MS/DNB/MDS) at AFMS institutions, subject to the priorities laid down in the ‘Information Bulletin for PG Courses in AFMS Institutions through NEET PG2024 and NEET MDS-2024’, is open to the graduates of medical/ dental colleges recognized by NMC/ DCI/ NDC and who have registered themselves as Registered medical/ dental practitioners with any State Medical/ Dental Council recognized by NMC/ DCI/ NDC. All candidates, except Priority-II, must be citizens of India.
Q2 What are the minimum qualifying criteria for interning students?
A Students who have completed/ are completing an internship on or before 30 Jun 2024 for MDS Courses as notified by NBE are eligible to apply/ register. However, the Provisional Registration Certificate / Permanent Registration Certificate should be available at the time of admission.
Q3 Do candidates of all priorities have to register with MCC?
A Yes, candidates of all priorities have to register on the MCC website for AFMS Institutions as per priority. Further, candidates under Priority-III, IV & V would also have to select and lock the preferred institute and seat as per instructions and schedule stipulated by the MCC.
Q4 What are the minimum qualifying criteria with respect to the NEET MDS exam and the score for all candidates?
A Appearance in the NEET MDS 2024 and securing the minimum marks as indicated by NBE.
Q5 What is the eligibility of a candidate who has ‘cancelled’/ ‘failed to report for admission within the stipulated time’/ ‘vacated a seat mid-course in the past’, which has resulted in lapse/ wastage of a seat in the past?
A A candidate shall not be eligible to take admission in AFMS Institutions if he/ she has ‘cancelled’/ ‘failed to report for admission within the stipulated time’/ ‘vacated a seat mid-course in the past’, which has resulted in lapse/ wastage of a seat.
Q6 What are the liabilities of a candidate vacating a seat mid-course in the past, which has resulted in lapse/ wastage of the said seat?
A The liabilities of vacating an allotted seat in respect of any candidate admitted under any priority on conclusion of the counselling will be as per the policy and directions of the NBE/ NMC/ DCI/ NDC/ MoHFW/ MCC/ DGAFMS/ affiliated University. Such a candidate will be liable to pay the University charges to which the college is affiliated and bond money as laid down in the Surety Bond executed at the time of admission as applicable.
Q7 What are the list of certificates to be submitted in original by the selected candidates at the AFMS PG Teaching Institute on the day of admission along with the same as a scanned (‘.pdf’ format) softcopy on a CD?
A i 06.
ii Six Passport size photographs.
ii NEET MDS 2024 Admit card and printed copy of the DGHS website registration slip.
iii NEET MDS 2024 rank card allotted by NBE.
iv Class X/ SSLC/ ICSE certificate as a valid certificate of proof of age.
v Nationality Certificate/ Xerox copy of valid passport/ Domicile Certificate (where applicable)/ Birth Certificate endorsed with INDIAN nationality on it.
vi First to Final year BDS Mark Sheets of the respective university. Priority – V candidates should have secured a min of 55% marks in the final BDS.
vii MBBS/ BDS Pass Certificate/Degree Certificate.
viii Internship Completion Certificate.
ix Permanent/ Provisional State Medical/ Dental Council registration certificate.
x Attempt Certificate.
xi Transfer Certificate/ Migration certificate.
xii Educational Gap affidavit, if any.
xiii Provisional allotment letter issued by the MCC.
xiv Priority – III candidates only: Permission to proceed on Study Leave from the employing/sponsoring organization is mandatory for Priority III candidates.
xv Priority – IV candidates – Release order from Armed Forces Medical Services and movement order from last unit for proceeding on release or NOC in case of SSC Officers in their last year of initial contractual service/ extended contractual service.
xvi Declaration by the candidate.
To view the notice, click the link below
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New Delhi- The National Board of Medical Examinations (NBEMS) has released the schedule for offline centralised merit-based counselling for international students- FNB Fellowship Programme for International Students (FPIS) courses for the 2023 admission session.
The Centralised Merit Based Counseling for admission to FNB (FPIS) courses for the 2023 Admission Session will be conducted by NBEMS via offline mode. Participation in the offline Counseling will be strictly followed as per the eligibility criteria for the FNB- FPIS 2023 Admission Session.
The schedule for the Counseling are as follows-
|
S.NO |
COUNSELLING PROCESS |
SCHEDULE |
|
1 |
Registration for Counseling. |
28-06-2024 to 01-07-2024 (1200 hrs). |
|
2 |
Submission of prescribed documents and seat choices (refer to para 5). |
28-06-2024 to 01-07-2024 (1200 hrs). |
|
3 |
Processing of eligibility and allotment. |
02-07-2024 to 03-07-2024. |
|
4 |
Result of seat allotment. |
03-07-2024 |
|
5 |
Payment of First Year Course fee and Submission of Indemnity Bond. |
03-07-2024 to 08-07-2024 (1700 hrs). |
|
6 |
Physical Joining at the allotted hospital. |
03-07-2024 to 12-07-2024 (1700 hrs). |
In addition, the Candidates are required to pay the Counseling registration fee of Rs. 2500/- to register for the counselling. Payment gateway charges, if any, shall be borne by the candidate. The registration fee for counselling will not be refunded under any circumstances once the candidate has been registered for Counseling. The registration fee shall be deposited in the account details mentioned in the notice.
Thereafter, the candidates are required to submit the following self-certified scanned copies of documents through email-
a MBBS/ Primary Medical Qualification Degree Certificate.
b Degree Certificate of postgraduate medical qualification equivalent to the eligible feeder issued on or before 31st December 2023.
c Post Graduate Medical Qualification Registration Certificate issued by the Medical Council of the respective country.
d No Objection Certificate issued by the Medical Council/ Government of the respective country for permission to work in India for the period of Fellowship.
e Temporary Registration with the National Medical Commission, New Delhi, India for the duration of the FNB course is to be submitted after seat allotment.
f Valid travel document (Passport) and valid permission (visa).
g Copy of receipt towards payment of Counseling fees.
h Declaration and Certification by the Candidate (cum Choice of Preferences) for opting for a seat – FET-2023-FPIS – 2023 Admission session(Click here for the format of the certificate for submitting the Choices of Preferences).
With this, the verification of documents will be done by NBEMS from 02 to 03 July 2024. Moreover, to participate in the counselling candidates need to follow certain steps which need to be completed-
1 Payment of registration fee for offline counselling.
2 Submission of prescribed documents.
3 Submission of Choices.
The seat allocation will be done in order of merit cum choice/ preference of seats indicated by the candidate during the registration/choice submission process and the provisional seat allotment result of the eligible candidates will be published on the NBEMS website.
To join the allotted seat, the candidate is required to pay the First-year course fee, which is nonrefundable within the stipulated time. After the payment of the First-year course fee, the seat allotted to him/her will be frozen in his/her favour. The details regarding the submission of the annual course fee will be communicated to the candidate in the seat allotment letter issued by NBEMS.
Along with this, NBE has also released an indicative seat matrix for FET-FPIS 2023. As per the seat matrix, there are a total of 28 vacant seats in 11 specialities.
SEAT MATRIX
|
S.NO |
SPECIALITY |
FPIS SEAT FOR 2023 ADMISSION SESSION |
|
1 |
Arthroplasty. |
4 |
|
2 |
Breast Imaging. |
1 |
|
3 |
Hand & Micro Surgery. |
1 |
|
4 |
Maternal & Foetal Medicine. |
1 |
|
5 |
Minimal Access Surgery. |
5 |
|
6 |
Neurovascular Intervention. |
1 |
|
7 |
Paediatric Hemato-Oncology. |
6 |
|
8 |
Reproductive Medicine. |
2 |
|
9 |
Spine Surgery. |
4 |
|
10 |
Trauma & Acute Care Surgery. |
1 |
|
11 |
Vitreo Retinal Surgery. |
2 |
Also, the candidates are required to submit the duly signed undertaking for an Indemnity Bond of Rs. 5,00,000/- before joining the Fellowship Programme.
To view the notice, click the link below
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Uttar Pradesh- Uttar Pradesh Director General, Medical Education & Training (UPDGME) has released certain important information/instructions regarding the online counselling of UP National Eligibility cum Entrance Test-Master of Dental Surgery (NEET MDS) 2024.
Below are the important information/instructions regarding the online counselling of UP NEET MDS 2024-
1 UPDGME will conduct the online counselling of UP NEET MDS-2024 in collaboration with the State Informatics Centre (NIC), a technical body nominated by the Government of Uttar Pradesh. Admission taken at the level of any unauthorised institution/person is completely illegal, for which the UPDGME will not be responsible.
2 All admissions taken by any unauthorised entity/individual or by self will be treated as completely illegal. If in future the office receives any complaint regarding such unauthorised entry then the entire responsibility will be of the candidate himself. On which the department will have no responsibility.
3 Only the candidates declared successful in the NEET MDS-2024 examination conducted by NBEMS are eligible to participate in the UP NEET MDS-2024 counselling process.
4 All information related to online counselling of UP NEET MDS-2024 will be displayed on the departmental official websites.
5 Candidates willing to take admission to private sector dental colleges should know about the respective colleges and the scholarships from the concerned college by themselves. Or the parents themselves should collect complete information at their own level. The Office, Government/Directorate General is not responsible for any reply or take any responsibility thereon.
6 Reservation Certificates of Other Backward Classes and Economically Weaker Sections (EWS) of Uttar Pradesh should be made on or after 01 April 2024. SC/ST/OBC/EWS category candidates are advised to collect the reservation certificate issued by the Government of Uttar Pradesh in an updated format to facilitate online verification of the certificate.
7 All certificates related to reservation (OBC, Scheduled Caste, Scheduled Tribe and Economically Weaker Section) (except Disability Certificate) issued by the competent authority of Uttar Pradesh on the format prescribed by the Government of Uttar Pradesh will be valid. However, any certificate regarding reservation not issued in the format prescribed by the Government of India will not be valid. Apart from Uttar Pradesh state, reserved category candidates from other states will be considered in the unreserved category.
8 For Disability Certificate for Persons with Disabilities a Disability Certificate issued by MCC/NMC designated centres will only be valid.
To view the instructions, click the link below
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Cambridge: AstraZeneca has announced the high-level results from the ADJUVANT BR.31 Phase III trial, sponsored by the Canadian Cancer Trials Group (CCTG), showed Imfinzi (durvalumab) did not achieve statistical significance for the primary endpoint of disease-free survival (DFS) versus placebo in early-stage (IB-IIIA) non-small cell lung cancer (NSCLC) after complete tumour resection in patients whose tumours express PD-L1 on 25% or more tumour cells.
Susan Galbraith, Executive Vice President, Oncology R&D, AstraZeneca, said, “We are disappointed in the ADJUVANT BR.31 results. Imfinzi has helped change the treatment landscape and achieved multiple positive Phase III trials for patients with earlier stages of lung cancer. We are committed to addressing the remaining unmet need in lung cancer through our broad development programme.”
The safety profile for Imfinzi was consistent with its known safety profile, and no new safety concerns were reported. The data will be shared at a forthcoming medical meeting.
Imfinzi is the only approved immunotherapy and the global standard of care in the curative-intent setting of unresectable, Stage III NSCLC in patients whose disease has not progressed after chemoradiotherapy based on the PACIFIC Phase III trial.
Imfinzi is also being investigated as monotherapy and in combinations in several other early-stage lung cancer settings, including in medically inoperable or unresected Stage I-II NSCLC (PACIFIC-4) and unresectable, Stage III NSCLC (PACIFIC-5, 8 and 9).
Read also: AstraZeneca Truqap, Faslodex combo approved in EU for advanced ER-positive breast cancer
Each year, there are an estimated 2.4 million people diagnosed with lung cancer globally. Lung cancer is the leading cause of cancer death among both men and women, accounting for about one-fifth of all cancer deaths. Lung cancer is broadly split into NSCLC and small cell lung cancer (SCLC), with 80-85% of patients diagnosed with NSCLC.
The majority of NSCLC patients are diagnosed with advanced disease while approximately 25-30% present with resectable disease at diagnosis. Early-stage lung cancer diagnoses are often only made when the cancer is found on imaging for an unrelated condition.
The majority of patients with resectable disease eventually develop recurrence despite complete tumour resection and adjuvant chemotherapy. Only around 58% of patients with Stage IB disease will survive for five years. This decreases to 36-46% for patients with Stage II and 24% for patients with Stage IIIA disease, reflecting a high unmet medical need.
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