Assistant Professor Post At UPSC In Health Ministry, Apply Now

New Delhi: The Union Public Service Commission (UPSC) has invited online applications for the Specialist Grade III Post Assistant Professor in the Department of Health and Family Welfare, Ministry of Health & Family Welfare on permanently in different dept.

UPSC is India’s premier central recruiting agency. It is responsible for appointments to and examinations for All India services and group A & group B of Central services.

UPSC Vacancy Details:

Total no. of Vacancies:- 40

The Vacancies are in the departments of Nephrology, Nuclear Medicine, Orthopaedics, Paediatric Cardiology, Paediatric Surgery, and Plastic and Reconstructive Surgery, Surgical Oncology, Urology.

Last Date of Application: 2nd May 2024.

For more details about Qualifications, Age, Pay Allowance, and much more, click on the given link:
https://medicaljob.in/jobs.php?post_type=&job_tags=upsc&location=&job_sector=all

HOW TO APPLY?

i) Candidates must apply online through the website http://www.upsconline.nic.in. Applications received through any other mode would not be accepted and summarily rejected.

ii) Candidates must upload the documents/certificates in support of all the claims made by them in the application like, Date of Birth, Experience (preferably in prescribed format), Desirable Qualification(s) etc. or any other information, separately against each claim in pdf file in such a way that the file size does not exceed 1 MB for the respective aforesaid modules and 2 MB for the “UPLOAD OTHER DOCUMENT” module and is legible when a printout taken. For that purpose, the applicant may scan the documents/certificates in 200 dpi grey scale. Documents like Pay Slip, Resume, Appointment Letter, Relieving Letter, Un-signed Experience Certificate etc. must not be uploaded in the Document Upload Module:-

a) Matriculation/10th Standard or equivalent certificate indicating date of birth, or mark sheet of Matriculation/10th Standard or equivalent issued by Central/State Board indicating Date of Birth in support of claim of age. Where date of birth is not available in certificate/mark sheets, issued by concerned Educational Boards, School leaving certificate indicating Date of Birth (in case of Tamil Nadu& Kerala).

b) Degree/Diploma certificate as proof of educational qualification claimed. In the absence of Degree/Diploma certificate, provisional certificate along with mark sheets pertaining to all the academic years.

c) Order/ letter in respect of equivalent Educational Qualifications claimed, indicating the Authority (with number and date) under which it has been so treated, in respect of equivalent clause in Essential Qualifications, if a candidate is claiming a particular qualification as equivalent qualification as per the requirement of advertisement.

d) Certificate(s) in the prescribed proforma from the Head(s) of Organization(s)/Department(s) for the entire experience claimed, clearly mentioning the duration of employment (date, month & year) indicating the basic pay and consolidated pay. The certificate(s) should also mention the nature of duties performed/experience obtained in the post(s) with duration(s). Experience Certificate should be issued in prescribed format relevant to the post. Experience certificate not in prescribed proforma but containing all the details as mentioned above would be considered on merits by the Commission.

e) Caste certificate by candidate seeking reservation as SC/ ST/ OBC, in the prescribed proforma from the competent authority indicating clearly the candidate’s Caste, the Act/ Order under which the Caste is recognized as SC/ ST/ OBC and the village/ town the candidate is ordinarily a resident of.

f) A declaration in the prescribed format by candidate seeking reservation as OBC, that he/she does not belong to the creamy layer on the crucial date, in addition to the community certificate (OBC). Unless specified otherwise, the prescribed closing date for receipt of Online Recruitment Application for the post is to be treated as crucial date.

g) Certificate of Disability in prescribed proforma issued by the competent authority to Persons with Benchmark Disabilities (PwBD) eligible for appointment to the post on the basis of prescribed standards of Medical Fitness. The Competent Authority to issue Certificate of Disability shall be a Medical Board duly constituted by the Central or a State Government. The Central/ State Government may constitute Medical Board(s) consisting of at least three members out of which at least one shall be a specialist in the particular field for assessing Locomotor/ Cerebral / Visual / Hearing disability, as the case may be.

h) Documentary support for any other claim(s) made.

Note: If any document/ certificate furnished is in a language other than Hindi or English, a transcript of the same duly attested by a Gazetted officer or notary is to be uploaded.

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Research shows ‘profound’ link between dietary choices and brain health

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Sri Sathya Sai Sanjeevani Hospitals completes 30000 free paediatric heart surgeries

Mumbai: Sri Sathya Sai Sanjeevani Hospitals in Mumbai, Maharashtra; Raipur, Chhattisgarh; and Palwal, Haryana recently marked a significant milestone of completing 30,000 free pediatric heart surgeries and interventions under the esteemed “Gift of Life” program.

Dr C Sreenivas, Chairman, and Shri Sunil Gavaskar, Trustee and Former Captain of the Indian Cricket Team, graced the celebrations, underscoring the hospital’s unwavering commitment to providing essential cardiac care to children nationwide, regardless of financial constraints.

The completion of 30,000 free-of-cost paediatric heart surgeries and interventions at Sri Sathya Sai Sanjeevani Hospitals highlights their steadfast dedication to offering the much-needed cardiac care to children across the country, irrespective of financial constraints. In a country where a child’s heart condition often brings not just medical concerns but also financial burdens, the hospital’s efforts resonate with a heartbeat of hope and humanity, reports news agency ANI.

Also Read:Sri Sathya Sai Health and Education Trust, The Hans Foundation collaborate for 300 cost-free heart surgeries for children

Furthermore, Sri Sathya Sai Sanjeevani Hospital inaugurated India’s pioneering free healthcare skill training program at the Sri Sathya Sai Sanjeevani Healthcare Skill Development Institute. This initiative offers a fully funded, one-year program tailored for 10th or 12th-grade students. Focused on training Medical & Surgical Assistants and Allied Healthcare Skills, the program not only imparts technical expertise but also nurtures personal development, empowering rural youth, particularly those from socio-economically disadvantaged backgrounds, across the nation.

Dr C Sreenivas, Chairman of the Sri Sathya Sai Health and Education Trust, while announcing completion of 30,000 surgeries expressed “Sri Sathya Sai Sanjeevani is built today on 30,000 stories of children with congenital heart disease and their families from across world. What started 12 years back as one hospital is today a Social Transformative Movement in the Service of the Nation. These children will grow into contributory citizens of Vikasit Bharath passing on the legacy of selfless love which they have received through Sri Sathya Sai Sanjeevani.”

“I am also happy to announce the launch of a totally free one-year program for students who have completed 10th or 12th grade at our Skill Development Institute. The program shall Educate- Empower and make the students employable in Healthcare sector which has high-demand role of Medical & Surgical Assistants and Allied Healthcare Skills. It is a nation building initiative through skilling rural youth in healthcare sector.” Dr C Sreenivas, Chairman of Sri Sathya Sai Health and Education Trust added further.

According to ANI report, Legendary cricketer and Trustee of Sri Sathya Sai Health & Education Trust, Sunil Gavaskar, who has sponsored hundreds of heart surgeries at Sathya Sai Sanjeevani, serves as a brand ambassador of the cause, amplifying stories of hope. Reflecting on the achievement, he said, ” I consider this as my third and most fulfilling innings of life as these children are getting a new healthy future through these totally free surgeries done at Sai Sanjeevani Hospitals. These children can be future successful sportsmen/sportswomen, artists or leaders of the world. I would urge all to be part of this transformative journey.”

With over 300,000 children born with heart disease annually in India, it remains a leading cause of infant mortality, often inaccessible to many. Among these, approximately 50,000 infants require urgent intervention within their first year. Sri Sathya Sai Sanjeevani Hospitals’ achievement of totally free of cost 30,000 surgeries and interventions isn’t just a milestone: it’s 30,000 children reclaiming their childhoods and families breathing freely.

Fuelled by donor compassion and staff dedication, their impact extends nationwide across 30 states and union territories in India and globally across eighteen countries. Their ‘Free of Cost’ care removes the crippling financial burden for families, ensuring holistic support from pre- to post-operation. Beyond medical prowess, the hospital embodies radical love in action, fostering genuine connections and healing not just hearts, but entire families.

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USFDA approves Biktarvy label update with data for pregnant adults with HIV: Gilead Sciences

Foster City: Gilead Sciences, Inc. has announced the U.S. Food and Drug Administration (FDA) has approved an updated label with additional data reinforcing the safety and efficacy profile of Biktarvy (bictegravir 50 mg/emtricitabine 200 mg/tenofovir alafenamide 25 mg tablets, B/F/TAF) to treat pregnant people with HIV-1 (PWH) with suppressed viral loads.

These additional data stem from Study 5310, which evaluated the pharmacokinetics, safety and efficacy of Biktarvy in pregnant PWH who have suppressed viral loads and no known resistance to any components of Biktarvy in their second and third trimesters and through a median of 16 weeks postpartum. This update makes Biktarvy the only second-generation integrase strand transfer inhibitor (INSTI)-based single-tablet regimen (STR) with in-label clinical trial data and FDA approval in virologically suppressed adults who are pregnant. The U.S. Department of Health and Human Services (DHHS) perinatal guidelines recognize Biktarvy as having sufficient data to support being recommended as an alternative complete regimen for use in pregnancy and for people who are trying to conceive. Additionally, guidelines recommend continuing Biktarvy for PWH already on treatment who are virologically suppressed and tolerating treatment well who may become pregnant.

“This label update marks an important milestone for Biktarvy, reinforcing its efficacy profile for pregnant PWH, an often understudied and most vulnerable community in clinical research,” said Jared Baeten, MD, PhD, Vice President, HIV Clinical Development, Gilead Sciences. “Not only is Biktarvy an alternative regimen for use in pregnancy, but people of childbearing potential can also remain on Biktarvy if they become pregnant. We continue to keep people at the center of our tireless commitment to HIV treatment research and development so that our medicines address the needs of the broad range of communities that we serve.”

The updated label now includes additional data from Study 5310, a Phase 1b, open-label, single-arm, multicenter clinical trial evaluating the pharmacokinetics, safety and efficacy of Biktarvy in pregnant PWH who were virologically suppressed (HIV-1 RNA < 50 copies/mL) and had no known resistance to the components of Biktarvy. Participants were administered Biktarvy once daily from the second or third trimester through postpartum. Lower plasma exposures of Biktarvy were observed during pregnancy as compared to postpartum; all 32 participants who completed the study maintained viral suppression during pregnancy, at delivery and through week 18 postpartum. The median CD4+ cell count at baseline was 558 cells/μL, and the median change in CD4+ cell count from baseline to week 12 postpartum was 159 cells/μL. All 29 newborn participants had negative/nondetectable HIV-1 PCR results at birth and/or at four to eight weeks post birth. Further, the study did not identify any new safety or tolerability concerns for people who use Biktarvy during pregnancy and postpartum as the overall incidence and types of adverse events observed were consistent with those expected for the population studied.

“This label update marks a significant milestone in Gilead’s efforts to address the individual needs of all people impacted by HIV, as these data can help to provide assurance for people of childbearing potential to remain on Biktarvy if they were to become pregnant. The Biktarvy label was also updated in February 2024 to align with Centers for Disease Control and Prevention (CDC) guidance on breastfeeding, which encourages a dialogue between a person and their healthcare provider regarding breastfeeding,” the release stated.

“As an OB-GYN and a longtime women’s health advocate, I’m incredibly passionate about helping end health disparities among women, and especially Black women who are disproportionately impacted by HIV,” said Yolanda M. Lawson, MD, President, National Medical Association. “I’m encouraged by the tremendous progress made in personalizing HIV treatment over the years, including this milestone that further supports the safety profile of Biktarvy use during pregnancy. Together, we can help bring all PWH the care they need, including those who are or may become pregnant, so they can continue to live longer, healthier lives while on HIV treatment.”

“These additional data can help to better inform treatment decisions between pregnant PWH and their providers and mark an incredible step forward in addressing the unique needs PWH have when they are pregnant or planning to become pregnant,” said William R. Short, MD, Associate Professor of Medicine, Perelman School of Medicine at the University of Pennsylvania. “As experts in perinatal care, we will continue to recommend ways pregnant PWH can maintain undetectable viral loads so they can stay healthy and prevent transmission to their baby.”

There is no cure for HIV or AIDS.

Biktarvy is a complete HIV treatment that combines three powerful medicines to form the smallest 3-drug, integrase strand transfer inhibitor (INSTI)-based single-tablet regimen (STR) available, offering simple once-daily dosing with or without food, with a limited drug interaction potential and a high barrier to resistance. Biktarvy combines the novel, unboosted INSTI bictegravir, with the Descovy  (emtricitabine 200 mg/tenofovir alafenamide 25 mg tablets, F/TAF) backbone. Biktarvy is a complete STR and should not be taken with other HIV medicines.

U.S. Indication for Biktarvy

Biktarvy (bictegravir 50 mg/emtricitabine 200 mg/tenofovir alafenamide 25 mg) is indicated as a complete regimen for the treatment of HIV-1 infection in adults and pediatric patients weighing at least 14 kg who have no antiretroviral (ARV) treatment history or to replace the current ARV regimen in those who are virologically-suppressed (HIV-1 RNA <50 copies per mL) on a stable ARV regimen with no known or suspected substitutions associated with resistance to bictegravir or tenofovir.

Read also: Gilead Sciences gets exclusive global license to develop, commercialize Xilio tumor-activated IL-12

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EMA Committee recommends nod for Bristol Myers Squibb Opdivo in combination with Cisplatin, Gemcitabine for Urothelial Carcinoma

Princeton: Bristol Myers Squibb has announced that the Committee for Medicinal Products for Human Use (CHMP) of the European Medicines Agency (EMA) has recommended approval of Opdivo (nivolumab) in combination with cisplatin and gemcitabine for the first-line treatment of adult patients with unresectable or metastatic urothelial carcinoma. The European Commission (EC), which has the authority to approve medicines for the European Union (EU), will now review the CHMP recommendation. The final EC decision is expected in June 2024.

“For eligible patients with unresectable or metastatic urothelial carcinoma, platinum-based chemotherapy in the first-line setting has been the standard of care for decades but the durability of response to chemotherapy alone is poor and once a patient progresses, treatment options become increasingly limited,” said Dana Walker, vice president and Global Program Lead, Genitourinary Cancers, Bristol Myers Squibb. “New treatment options that may improve responses, delay disease progression, and offer survival benefit in the first-line setting are needed. With today’s CHMP positive opinion, we are one step closer to potentially providing eligible patients with unresectable or metastatic urothelial carcinoma in the European Union with a new first-line treatment option.”

The positive CHMP opinion is based on results from a sub-study of the CheckMate -901 trial which were presented at the European Society of Medical Oncology (ESMO) Congress 2023. In the sub-study, Opdivo in combination with cisplatin and gemcitabine followed by Opdivo monotherapy demonstrated statistically significant and clinically meaningful improvements in the primary efficacy endpoints of overall survival (OS) and progression-free survival (PFS) as assessed by Blinded Independent Central Review (BICR). With a median follow up of approximately 33 months, treatment with Opdivo in combination with cisplatin and gemcitabine reduced the risk of death by 22%, demonstrating a median OS of 21.7 months versus 18.9 months with cisplatin-gemcitabine alone (Hazard Ratio [HR] 0.78; 95% Confidence Interval [CI]: 0.63, 0.96; p=0.0171). Patients receiving Opdivo in combination with cisplatin and gemcitabine had their risk of disease progression or death reduced by 28%, with a median PFS of 7.9 months compared to 7.6 months with cisplatin-gemcitabine alone (HR 0.72; 95% CI: 0.59, 0.88; p=0.0012). The safety profile was consistent with the known safety profiles of the individual components of the regimen. No new safety concerns were identified.

CheckMate -901 is the first Phase 3 trial with an immunotherapy-chemotherapy combination to demonstrate a survival benefit compared to standard-of-care chemotherapy alone in the first-line treatment of adults with unresectable or metastatic urothelial carcinoma.

On March 7, 2024 the U.S. Food and Drug Administration (FDA) approved the use of Opdivo in combination with cisplatin and gemcitabine as a first-line treatment for adult patients with unresectable or metastatic urothelial carcinoma, following a Priority Review. Opdivo and Opdivo-based combinations have shown significant improvements in OS in Phase 3 clinical trials across multiple tumors, including urothelial carcinoma, renal cell carcinoma, non-small cell lung cancer, malignant pleural mesothelioma, melanoma, hepatocellular carcinoma, gastric cancer, squamous cell carcinoma of the head and neck and esophageal squamous cell carcinoma.

Read also: Bristol Myers Squibb Reblozyl gets expanded European nod for anemia in lower risk Myelodysplastic Syndromes

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Amidst rising temperature, Tamil Nadu doctor share tips for pregnant women, newborn babies

Salem: The Indian Meteorological Department (IMD) has issued warnings of heat wave to severe heat wave conditions across various regions, including Gangetic West Bengal, Sub Himalayan West Bengal, north Odisha, East Uttar Pradesh, Bihar, Jharkhand, Rayalaseema, Telangana, Tamil Nadu, Puducherry & Karaikal, and Kerala for April 27 to 28.

IMD, in a post of X on Friday said, “Heat wave to severe heat wave conditions very likely in many pockets of Gangetic West Bengal, in isolated pockets of Sub Himalayan West Bengal, few pockets of north Odisha and heat wave conditions very likely in East Uttar Pradesh, Bihar, Jharkhand, Rayalaseema, Telangana, Tamil Nadu, Puducherry & Karaikal, Kerala & Mahe and interior Karnataka for April 27 and April 28.”

In an interview with ANI, Dr Anusuya, who is a child specialist at Arogya Women Centre in Tamil Nadu’s Salem shared tips to cope and stay safe in extreme heat and ways of taking care of pregnant women, newborn babies and young kids.

Also Read:Heatwave Alert: Telangana issues heatwave advisory for public

“They should wear only cotton garments and should avoid coming out of their houses during 10:00 am to 4:00 pm. They should try to intake more fluids in the form of buttermilk or tender coconut water and increase the consumption of water-containing fruits like cucumber and watermelon. It is important for them to increase their water intake to maintain the fluid content in their uterus also,” Dr Anusuya told ANI.

She further added, “Excessive sweat can lead to skin problems like fungal infections. And therefore, they should wear cotton clothes.”

For newborn babies, Dr Anusuya advises mothers to notice how much urine the baby is passing in a day. “Excessive sweat can cause skin problems and dehydration. So, it’s important for the mothers to notice how much urine the baby passes in a day. If the baby doesn’t pass urine for more than a day, then the baby is dehydrated,” she said.

The doctor also has advised mothers to make their babies wear only cotton clothes and bath them twice or thrice a day.

Regarding young children, the doctor cautioned against outdoor activities during peak heat hours (10:00 am to 4:00 pm). Instead, she suggested indoor play or staying in shaded areas, coupled with increased water intake to prevent dehydration.

“They should either play indoors or play in the shade and should increase the intake of water,” she said.

The IMD has also said that heat wave to severe heat wave conditions is likely to continue over East and South peninsular India for the next five days.

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