COVID 19 cases jump 52 per cent globally in past one month: WHO

New Delhi: The global number of new Covid-19 cases has increased by 52 per cent during the last one month, the World Health Organization (WHO) said on Saturday.

In the latest epidemiological update on Friday, the UN health body reported over 850,000 new cases worldwide in the 28-day period from November 20 to December 17.

The number of new deaths decreased by 8 per cent as compared to the previous 28-day period, with over 3,000 new fatalities reported. As of December 17, over 772 million confirmed cases and nearly seven million deaths have been reported globally. 

Also Read:COVID-19 sub-variant JN.1: Safdarjung Hospital doctors advise precautions

During the period from November 13 to December 10, over 118,000 new Covid hospitalisations and over 1,600 new intensive care unit (ICU) admissions have been recorded with an overall increase of 23 per cent and 51 per cent respectively amongst the countries reporting consistently within the current and past reporting periods.

WHO last week designated JN.1, a sub-lineage of BA.2.86 Omicron variant, as a separate variant of interest (VOI) apart from its parent lineage BA.2.86 due to its rapid increase in prevalence in recent weeks.

However, EG.5 remains to be the most reported VOI globally.

At the global level, during the past 28 days, a total of 118,958 new hospitalisations and 1,610 new intensive care unit (ICU) admissions were reported from 58 and 36 countries, respectively.

The South-East Asia Region reported over 9,200 new cases, a 388 per cent increase as compared to the previous 28-day period.

The highest numbers of new cases were reported from Indonesia (3,725), followed by India (3,241) and Thailand (2,120).

The number of new 28-day deaths in the Region increased by 317 per cent as compared to the previous 28-day period, with 50 new deaths reported.

The highest numbers of new deaths were reported from India (21 new deaths), Thailand (16 new deaths) and Indonesia (12 new deaths).

The WHO emphasised that current vaccines continue to provide protection against severe disease and death from the JN.1 variant and other circulating variants of SARS-CoV-2. The organisation is closely monitoring the evidence and will update the risk evaluation of JN.1 as needed.

To mitigate the spread of these respiratory illnesses, the WHO advised individuals to adopt preventive measures, including wearing masks in crowded or poorly ventilated areas, maintaining a safe distance, practising respiratory etiquette, regular hand hygiene, and getting tested for Covid or influenza if symptoms arise or after exposure.

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Health Bulletin 23/December/2023

Here are the top health stories for the day:

Provisional Results of NEET SS Round 2 Counselling released

The Medical Counselling Committee (MCC) has released the Provisional Result for Round-2 of NEET SS Counselling 2023 (for D.M/ M.Ch/ DNB SS Courses). The provisional seat allotment result includes Rank, Qualifying Exam, Allotted Institute, Course and Remarks.

For more details, check out the link given below:

Provisional Results Of NEET SS Round 2 Counselling Released

Apollo Hospital held liable for not disclosing treatment cost, directed Rs 13 lakh compensation

Opining that not disclosing the quantum of money required for treatment on the part of the hospital amounts to unfair trade, the District Consumer Disputes Redressal Commission, Cuttack recently held Apollo Hospitals, Chennai deficient in their service towards a patient undergoing treatment at the facility.

With this observation, the consumer court has directed the hospital and its treating doctor to pay Rs 13 lakhs as compensation to the complainants for their mental agony and harassment and further a sum of Rs 30,000 towards cost of their litigation.

For more details, check out the link given below:

Apollo Hospital Held Liable For Not Disclosing Treatment Cost, Directed Rs 13 Lakh Compensation

PG medico suicide case: Kerala HC grants bail to doctor accused of dowry demands

In a significant development, the Kerala High Court on Friday, approved the bail application of a doctor who had faced suspension from the Indian Medical Association (IMA) following accusations of abetting the suicide of his girlfriend.

Medical Dialogues team had earlier reported that the victim, a second-year postgraduate surgery trainee at Government Medical College, Thiruvananthapuram, took her own life after the accused cancelled their wedding plans due to alleged dowry demands.

For more details, check out the link given below:

PG Medico Suicide Case: Kerala HC Grants Bail To Doctor Accused Of Dowry Demands


NMC asks universities to inform on MBBS internship completion date of 2018 batch

Considering that the pandemic affected the schedule for admission and completion of MBBS courses, including the mandatory internship, the National Medical Commission (NMC) has now asked the medical universities to submit details regarding the Internship completion date of 2018 batch MBBS students.

Informing the medical universities that the Medical Counselling Committee (MCC) has asked them to submit the details, NMC has provided the link to the Google Form and asked the medical and health universities across the country to fill the form by 25.12.2023.

For more details, check out the link given below:

NMC Asks Universities To Inform On MBBS Internship Completion Date Of 2018 Batch

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Pay Rs 20 crore or we will blow up your Clinic: Bihar Pediatrician gets extortion threat

Begusarai: In another shocking case of rangdari (extortion) in Bihar, a child specialist from Begusarai has received an extortion demand of Rs 20 crore by post. In the extortion demand, sent through Speed Post, the sender asked the doctor to pay the amount within 8 days otherwise his clinic would be blown up.

A case has been registered against the culprits, and an investigation is underway. The doctor has been identified as Dr Rupesh Kumar, a child specialist who runs a clinic in Begusarai. The demand was made through a letter sent by speed post on Thursday. The distressed doctor along with IMA Chairman, Dr Ranjan Kumar Chaudhary and a group of doctors, met SP Yogendra Kumar on Friday and sought help from him.

“The letter was received by my staff and handed over to me. When I opened the envelope and read the letter, I went into shock. I immediately informed local police and IMA officials about the incident,” said Dr Rupesh Kumar. A copy of the letter has been shared by Aj Tak where the sender introduced himself as one Bumbum Kumar from the village called Jagdishpur in Begusarai. The sender mentioned the name of a Thakur gang and claimed to be a part of it. In the letter, he stated, “if our demands are not fulfilled within 8 days, by the 9th day, the gang will blow up your clinic.” 

Threatening the doctor, the letter stated that there would be bloodshed and they would make it impossible for the doctor to go outside Begusarai if he refuses to pay Rs 20 crore to the gang. According to IANS, SP Yogendra Kumar said: “We have registered an FIR in this matter in the town police station based on the complaint given by the victim and the contents of the letter. Preliminary investigation revealed that a criminal from a village who comes under Ballia police station sent the letter by registered Speed Post. We are making efforts to nab him.” 

Rangdari cases, characterized by extortion and intimidation, are unfortunately becoming more prevalent in many states including Bihar, posing a growing concern for the safety and security of doctors. A similar case of rangdari occurred in Bihar a few months back also when a prominent doctor from Motihari town of Bihar was faced with an extortion threat asking him to cough up Rs 2 crore and threatening to kill him and his family members if the demands were not met in a couple of days. Following a similar pattern, the doctor also received an extortion letter, and the victim was running the Kavi Diagnostic Centre in the Chatauni locality of the city. 


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BMC’s COVID Centre Scam: ED attaches assets worth over Rs 12 cr

New Delhi: The Directorate of Enforcement (ED) has attached assets worth more than Rs 12 crore belonging to a number of people, including Sujit Patkar, as part of a money laundering probe, the officials said on Friday. 

The federal agency’s investigation is linked to an alleged fraud in setting up of Brihanmumbai Municipal Corporation (BMC)-run Covid care centres in Mumbai.

The assets belong to the partners of Lifeline Hospital Management Services and their alleged accomplices.

Also Read:Maha: Hospital treats COVID patients without permission, sealed

The attached assets are in the form of 3 flats in Mumbai, mutual fund units and balances in bank accounts, as per the agency’s official statement.

The action has been taken against partners of Lifeline Hospital Management Services — Sujit Patkar, Dr Hemant Gupta, Rajeev Salunkhe, Sanjay Shah and their accomplices Sunil Kadam, alias Bala Kadam, ED said in a statement.

The total value of the attached properties is Rs 12.24 crore. 

The probe pertains to alleged irregularities in the Jumbo Covid facilities located at Dahisar and Worli. The money laundering case stems from an FIR of the Mumbai Police.

Based on the FIR registered by Azad Maidan Police station, Mumbai under sections 420, 406, 465, 467, 468, 471 and 304A of the Indian Penal Code, the ED initiated an investigation by recording ECIR under the Prevention of Money Laundering Act, 2002 (PMLA) in the case of Covid Scam of Rs. 32.44 Crore, the agency said.

Patkar and Dr Kishore Bisure, ex-dean from the BMC at the Dahisar Jumbo Covid Centre, were arrested by the agency in July and they are currently lodged in a jail under judicial custody.

It further said that the investigation by the agency revealed that during June 2020 MCGM had floated tenders and contracts for manpower supply at various Jumbo Covid facilities for ICU beds, oxygenated beds and non-oxygenated beds in Mumbai through Expression of Interest (EOI) on June 22, 2020, and on June 25, 2020, Lifeline Hospital Management services obtained tender for supply of staff members i.e., doctors, nurses, multi-purpose workers (ward boys, aayas and doctor assistant) and technicians to Jumbo Covid facilities at Dahisar and Worli for the period from July 2020 to February 2022 based on incomplete and false documents.

It is further revealed that during the service period, the EOI conditions were not maintained by the partners of Lifeline Hospital Management Services, and there was a huge under-deployment of staff members.

However, the invoices were submitted by showing adequate staff attendance as per the EOI conditions through fake and fabricated attendance sheets and staff records at the Dahisar Jumbo Covid facility.

Further, no records of attendance or staff data were submitted for Worli Covid Centres by the said firm.

Despite the same, the partners of Lifeline, in connivance with BMC staff, managed to clear the invoices and received Rs 32,44,86,784.9 from MCGM Authorities from September 2020 to June 2022.

Money trail investigations under PMLA revealed that after receipt of the amount from BMC Sujit Patker and other partners of Lifeline Hospital Management Services, it has diverted for buying assets, repaying housing loans, investing in real estate etc, the agency added.

All these identified assets in the form of flats, mutual fund units and bank balances in two bank accounts, totalling Rs 12.23 crore, have been provisionally attached under Section 5 of PMLA, 2002. Further investigation into this case is underway, it added.

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Fact Check: NMC letter recognising CPS courses for doctors undergoing training is fake

The letter bearing the signature of the Under Secretary of NMC PG Board and claiming that CPS degrees are recognised for the students undergoing training is FAKE, the National Medical Commission (NMC) has recently clarified.

Issuing a notice on December 14, 2023, the Apex Medical Commission has warned the doctors against the fake letter. With this, the Commission has once again its stand regarding the recognition of the controversial College and Physicians and Surgeons (CPS) courses.

For more details, check out the link given below:

Fact Check: NMC Letter Recognising CPS Courses For Doctors Undergoing Training Is FAKE

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Cold season beware of RSV, COVID, pink eye, stomach viruses, say researchers

Winter with cold air is a home for several infections, this season microbes breed causing a rush in hospitals and emergency departments specifically in metro cities.

“COVID is surging in all counties just in time for the holidays,” said MinuteClinic family nurse practitioner Sara Kayser. “Influenza cases are showing their presence as well, and strep throat and URIs are also on the rise.”

WAYNE COUNTY-RSV, Covid, influenza, strep throat, pink eye, coughs.

Dr. Christopher Loewe, Ascension St. John:

“I’m seeing more children with respiratory syncytial virus infection(RSV) and COVID-19. Now is the time to clean frequently touched surfaces such as doorknobs and mobile devices often. Washing your hands will also help protect you from germs. I’m seeing influenza in both kids and adults.”

Dr. Tiffney Widner, Children’s Hospital of Michigan pediatrician:

“With RSV, it is ramping up. But I don’t think we’re having any excessive problems; it’s just a typical season. It doesn’t seem like it’s a lot. We’re also seeing Flu A. Sometimes we’ll see Flu A first then Flu B, sometimes it flips. There’s not a rhyme or reason as to when it pops up, and we treat them the same.

If people think they have flu and they’re looking for a treatment, they should address it early. You need to treat it within two days of symptoms for it to have an effect. So if they have high-risk kiddos, they should be seen by their primary care physician or pediatrician if they have upper respiratory infection symptoms. Then their PCP can determine whether or not they need treatment.”

Dr. Jennifer Stevenson, Emergency Department, Henry Ford Medical Center Fairlane:

“At Fairlane, we’re seeing more and more COVID-19, consistent with the local/national trends. Also, influenza and RSV numbers are on the rise, along with other viral respiratory illness that we can’t specifically identify as readily. There continues to be a significant amount of strep throat in the community as well. Going into the holiday, consider having home COVID-19 tests available (they’re available from the government) and if you’re feeling ill, please test prior to gathering with family and friends. Many are experiencing milder symptoms with covid, though there are vulnerable populations who continue to be at risk. We’re also seeing more patients requiring hospital admission with influenza. If you’re feeling ill and must go out, please consider wearing a mask around others. For your protection, as your immune system is likely stressed, and to protect those around you. No one wants to be sick during the holidays!”

Dr. Zafar Shamoon, Chief of the Emergency Department, Corewell Health’s Beaumont Hospital, Dearborn:

“We have seen an uptick in RSV in a lot of kids and adults. We’ve also seen a lot of individuals coming in for a common cold/cough. There were a number of slip and fall cases last week with the ice. Now is a good time to check your carbon monoxide detector to make sure it’s working properly.”

OAKLAND COUNTY -– Upper respiratory infections, Covid, influenza, stomach viruses, RSV, mononucleosis.

Dr. Steven McGraw, Chair of Emergency Medicine, Ascension Providence Hospital, Novi & Southfield Campus:

“I’m seeing a large number of patients with upper respiratory infections including COVID-19 as people start to gather over the holidays. I’m also seeing patients with influenzae and stomach flu. A few other illnesses on the rise are strep throat, pneumonia and sinusitis. This is a reminder to wash your hands and get the flu shot. Over the holidays, people should be aware of the amount of alcohol they consume. Our rate of alcohol related accidents increases during this time.”

Dr. Whitney Minnock, Chief of Pediatrics, Corewell Health William Beaumont University Hospital in Royal Oak:

“We are seeing a lot of RSV, bronchiolitis and other respiratory viruses at this time. It’s very busy in our pediatric department.”

Henry Ford West Bloomfield Hospital Emergency Department:

“Here in the Emergency Department, we are seeing an uptick of fever/flu/COVID-19. We have also seen an increase in the amount of shortness of breath/respiratory issues and some chest pain.”

WASHTENAW COUNTY -– Influenza, RSV, Covid, respiratory viruses, stomach viruses.

Dr. Brad Uren, Clinical Associate Professor of Emergency Medicine, Michigan Medicine:

“Seeing flu, RSV, Covid, and other respiratory viruses this week. Some do require admission to the hospital. Some GI, but not a lot.”

Washtenaw County Health Department:

“Influenza cases in Washtenaw County residents are increasing. Most Influenza cases being reported in Washtenaw County are Influenza A, types A(H1N1) and A(H3). Sporadic cases of Influenza B are being reported. Flu-related hospitalizations of Washtenaw residents are currently increasing.”

MONROE COUNTY –- Shortness of breath, respiratory viruses, influenza, Covid, RSV.

MACOMB COUNTY –- Influenza, stomach viruses, upper respiratory infections, sore throat, Covid, bronchitis.

Dr. Anthony Joslin, Emergency physician at McLaren Macomb:

“There has been a sharp increase in influenza cases, presenting with symptoms of cough, fever, and body aches. The number of positive COVID-19 cases has increased slightly, with the majority of patients experiencing mild, treatable symptoms and not requiring hospitalization. There has been a significant increase cases of viral gastroenteritis and symptoms of nausea, vomiting, and diarrhea.”

Dr. Maria Samuel, Primary Care Physician, Henry Ford Medical Center Sterling Heights:

“We are seeing various upper respiratory infections, sore throat and especially COVID-19 infections this week. Vaccinated individuals present with less severe symptoms and recover faster, too. Although we are seeing prolonged coughing very frequently.”

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Lupin to buy established products portfolio in Europe, Canada from Sanofi for Rs 91 crore

New Delhi: Home-grown pharma major Lupin Ltd has said it acquired a portfolio of established products in Europe and Canada from Sanofi for a purchase consideration of EUR 10 million (Rs 91 crore).

Lupin Atlantis Holdings SA, Switzerland, a wholly-owned subsidiary of the company, has signed an asset purchase agreement with Sanofi, a French multinational pharmaceutical and healthcare company, for the purpose, Lupin said in a regulatory filing.

The purchase consideration is EUR 10 million (Rs 91 crore) plus sales milestones up to EUR 8 million (Rs 72.8 crore), contingent upon future sales, it added.
Under the agreement, Lupin will acquire brands AARANE in Germany and NALCROM in Canada and the Netherlands. The turnover of the said brands in these markets for the year ended March 31, 2023 was about USD 6.494 million (Rs 53.7 crore), the company said.
“The proposed transaction is of strategic interest by bringing accretive assets in the respiratory field to help structure the company’s new respiratory franchise in Germany following the launch of LUFORBEC in Germany, the launch of Gx SPIRIVA and the acquisition of XOPENEX and BROVANA in the US,” it added.
The transaction will require approval of the Foreign Direct Investment Bureau of Canada and is planned to be completed by the first quarter of 2024, Lupin said.

Lupin is an innovation-led transnational pharmaceutical company headquartered in Mumbai, India. The Company develops and commercializes a wide range of branded and generic formulations, biotechnology products, and APIs in over 100 markets in the U.S., India, South Africa, and across the Asia Pacific (APAC), Latin America (LATAM), Europe, and Middle East regions. The Company specializes in the cardiovascular, anti-diabetic, and respiratory segments and has a significant presence in the anti-infective, gastro-intestinal (GI), central nervous system (CNS), and women’s health areas. The company invested 7.9% of its revenue in research and development in FY23. Lupin has 15 manufacturing sites, 7 research centers.

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WHO adds SII-Oxford University Malaria vaccine to its list of prequalified vaccines

Geneva: WHO has added the R21/Matrix-M malaria vaccine to its list of prequalified vaccines. In October 2023, WHO recommended its use for the prevention of malaria in children following the advice of the WHO Strategic Advisory Group of Experts (SAGE) on Immunization and the Malaria Policy Advisory Group.

Read also: Serum Institute-Oxford University malaria vaccine bags WHO recommendation

The prequalification means larger access to vaccines as a key tool to prevent malaria in children with it being a prerequisite for vaccine procurement by UNICEF and funding support for deployment by Gavi, the Vaccine Alliance.

The R21 vaccine is the second malaria vaccine prequalified by WHO, following the RTS,S/AS01 vaccine which obtained prequalification status in July 2022. Both vaccines are shown to be safe and effective in clinical trials, for preventing malaria in children. When implemented broadly, along with other recommended malaria control interventions, they are expected to have a high public health impact.

Malaria, a mosquito-borne disease, places a particularly high burden on children in the African Region, where nearly half a million children die from the disease each year. Globally, in 2022, there were an estimated 249 million malaria cases and 608 000 malaria deaths across 85 countries.

The prequalification of the world’s second malaria vaccine, developed by Oxford University and manufactured by Serum Institute of India, is poised to expand access to malaria prevention through vaccination. Demand for malaria vaccines is high but the supply has thus far been limited. The availability of two WHO recommended and prequalified malaria vaccines is expected to increase supply to meet the high demand from African countries and result in sufficient vaccine doses to benefit all children living in areas where malaria is a significant public health risk.

Dr Rogério Gaspar, Director of the Department of Regulation and Prequalification at WHO said, “Achieving WHO vaccine prequalification ensures that vaccines used in global immunization programmes are safe and effective within their conditions of use in the targeted health systems. WHO evaluates multiple products for prequalification each year and core to this work is ensuring greater access to safe, effective and quality health products”.

Dr Kate O’Brien, Director of WHO’s Department of Immunization, Vaccines and Biologicals, said, “Today marks a huge stride in global health as we welcome the prequalification of R21/Matrix-M, the second malaria vaccine recommended for children in malaria endemic areas. This achievement underscores our relentless commitment to wiping out malaria which remains a formidable foe causing child suffering and death. This is another step toward ensuring a healthier, more resilient future for those who have lived for too long in fear of what malaria could do to their children. Together with our partners we are united in the pursuit of a malaria-free future, where every life is shielded from the threat of this disease.”

As part of the prequalification process, WHO applies international standards to comprehensively evaluate and determine whether vaccines are safe, effective and manufactured to international standards. WHO also ensures the continued safety and efficacy of prequalified vaccines through, for example, regular re-evaluation, site inspection and targeted testing. Prequalification supports the specific needs of national immunization programmes with regards to vaccine characteristics such as potency, thermostability, presentation, labelling and shipping conditions

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Medical Bulletin 23/December/2023

Here are the top medical news of the day:

Brain lesions in former football players linked to vascular, brain changes

Signs of injury to the brain’s white matter called white matter hyperintensities, as seen on brain scans, may be tied more strongly to vascular risk factors, brain shrinkage, and other markers of dementia in former tackle football players than in those who did not play football, according to a study published in the December 20, 2023, online issue of Neurology, the medical journal of the American Academy of Neurology.

“Studies have shown that athletes exposed to repetitive head impacts can have increased white matter hyperintensity burden in their brains,” said study author Michael L. Alosco, PhD, of Boston University Chobanian & Avedisian School of Medicine. “White matter hyperintensities are easily seen on MRI as markers of injury of various causes. We know these markers are more common as people age and with medical conditions such as high blood pressure, but these results provide initial insight that they may be related to multiple aspects of brain damage from repetitive head impacts.”

Reference: Brain lesions in former football players linked to vascular, brain changes; Neurology

Study: Spinal cord injury causes acute and systemic muscle wasting

Acute spinal cord injury (SCI) patients lose body weight and muscle mass, despite being on a high-calorie diet while in the intensive care unit. Their muscle wasting is substantial and extends beyond what can explained by inactivity or denervation (loss of nerve supply) alone.

Research led by The Ohio State University Wexner Medical Center and College of Medicine published in the journal Science Translational Medicine sheds new light and decodes early muscle loss after SCI to provide an unprecedent first understanding that muscle wasting.

Reference: Study: Spinal cord injury causes acute and systemic muscle wasting; Science Translational Medicine, DOI: 10.1126/scitranslmed.adh2156

Women’s risk of infertility increases by 3% for every Kg of weight gained

Obesity has significant implications for fertility and reproductive health. However, evidences linking abdominal obesity to female infertility were limited and inconclusive. Our objective was to figure out the potential relationship between waist circumference (WC) and infertility among women of childbearing age in the United States using data from the National Health and Nutrition Examination Survey (NHANES).

Researchers conducted cross-sectional study included 3239 female participants aged 18–45 years. To explore the independent relationship between WC and female infertility, the weighted multivariable logistic regression and smoothed curve fitting were performed. Interaction and subgroup analyzes were then conducted for secondary analysis.

Reference: Ke J, Feng Y, Chen Z (2023) Association between waist circumference and female infertility in the United States. PLoS ONE 18(12): e0295360. https://doi.org/10.1371/journal.pone.0295360

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Just In: MCC releases Final Results For NEET SS Round 2 Counselling

Delhi: The Medical Counselling Committee (MCC) has released the Final Result for Round-2 of NEET SS Counselling 2023 (for D.M/ M.Ch/ DNB SS Courses).

The provisional seat allotment result includes Rank, Qualifying Exam, Allotted Institute, Course and Remarks. To view the list, click on the link below –

https://medicaldialogues.in/pdf_upload/2023122398-228584.pdf

The candidates can now approach the allotted college/institute only after the declaration of the Final Result and only after downloading the allotment letter from the MCC website.

Recently, the provisional allotment results were announced. If any discrepancy in the result was found, the candidates were asked to inform to MCC of DGHS up to 12:00 Noon of 23.12.2023 through email on the Email id: mccresultquery@gmail.com.

The Medical Counselling Committee (MCC) is an organisation under the Directorate General of Health Services (DGHS) affiliated to the Ministry of Health and Family Welfare, Government of India and responsible for allotting seats for undergraduate, postgraduate and super-speciality medical and dental courses in government-run/aided colleges and deemed-to-be-university colleges. It allots seats online on the basis of the candidate’s score in the National Eligibility cum Entrance Test (NEET). Factors considered during allotment are merit, reservation eligibility and the preference list submitted by the candidate.

Also Read:Provisional Results Of NEET SS Round 2 Counselling released

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